Suppressive effect of fluticasone propionate on MMP expression in the nasal mucosa of allergic rhinitis patients in vivo

Y Kyo, KI Kanai, K Asano, T Hisamitsu, H Suzaki - in vivo, 2006 - iv.iiarjournals.org
The effects of intranasal corticosteroids on matrix metalloproteinases (MMPs) and their
inhibitors (tissue inhibitors of metalloproteinases (TIMPs)) in the nasal mucosa of patients …

Matrix metalloproteinases and their inhibitors in the nasal mucosa of patients with perennial allergic rhinitis

A Shaida, G Kenyon, J Devalia, RJ Davies… - Journal of allergy and …, 2001 - Elsevier
Background: Allergic rhinitis and asthma show many similarities in their epithelial and
inflammatory responses to allergens. However, one notable difference is that disruption and …

Expression of MMP-9 and TIMP-1 in the nasal mucosa of allergic rhinitis

HM LEE, JH CHOI, CS CHOI… - Korean Journal of …, 2000 - pesquisa.bvsalud.org
OBJECTIVES: Allergic rhinitis is characterized by airway structural changes, including
inflammation and basement thickening. An imbalance between matrix metalloproteinases …

Suppression of matrix metalloproteinase production in nasal fibroblasts by tranilast, an antiallergic agent, in vitro

T Shimizu, K Kanai, K Asano, T Hisamitsu… - Mediators of …, 2005 - hindawi.com
Allergic rhinitis is an inflammatory disease characterized by nasal wall remodeling with
intense infiltration of eosinophils and mast cells/basophils. Matrix metalloproteinases …

Effects of inhaled corticosteroids on metalloproteinase-8 and tissue inhibitor of metalloproteinase-1 in the airways of asthmatic children

Y Obase, P Rytilä, T Metso, AS Pelkonen… - International archives of …, 2010 - karger.com
Background: The effects of corticosteroids on the level and expression of matrix
metalloproteinase-8 (MMP-8; collagenase-2) and tissue inhibitors of metalloproteinases …

[HTML][HTML] Expression and roles of MMP-2, MMP-9, MMP-13, TIMP-1, and TIMP-2 in allergic nasal mucosa

S Mori, R Pawankar, C Ozu, M Nonaka… - Allergy, asthma & …, 2012 - ncbi.nlm.nih.gov
Purpose Allergic rhinitis (AR) and asthma share many characteristics, but structural changes
are observed far less often in AR. Matrix metalloproteinases (MMPs) constitute a family of Zn …

Suppressive activity of fexofenadine hydrochloride on metalloproteinase production from nasal fibroblasts in vitro

K Asano, KI Kanai, H Suzaki - Clinical & Experimental Allergy, 2004 - Wiley Online Library
Background Allergic rhinitis (AR) is an inflammatory disease characterized by nasal wall
remodelling with intense infiltration of eosinophils and mast cells/basophils. Matrix …

Inhibition of matrix metalloproteinases prevents allergen-induced airway inflammation in a murine model of asthma

K Kumagai, I Ohno, S Okada, Y Ohkawara… - The Journal of …, 1999 - journals.aai.org
Although matrix metalloproteinases (MMPs) have been reported to play crucial roles in the
migration of inflammatory cells through basement membrane components in vitro, the role of …

Suppression of matrix metalloproteinase production from nasal fibroblasts by fluticasone propionate in vitro

M Namba, K Asano, KI Kanai, Y Kyo… - Acta oto …, 2004 - Taylor & Francis
Objective—To examine the influence of fluticasone propionate (FP) on matrix
metalloproteinase (MMP) production from nasal polyp fibroblasts in vitro. Material and …

Matrix metalloproteinases and tissue inhibitors of metalloproteinases in nasal lavage after an inhalation challenge with flour

R Castano, D Miedinger, K Maghni… - The …, 2012 - Wiley Online Library
Abstract Objectives/Hypothesis: The existence of nasal mucosa remodeling in allergic
rhinitis is controversial. Few data are available on the dynamics of matrix metalloproteinases …