Hydrogen sulphide and nitric oxide cooperate in cardioprotection against ischemia/reperfusion injury in isolated rat heart

S Ustunova, S Takir, N Yilmazer, H Bulut, D Altindirek… - in vivo, 2020 - iv.iiarjournals.org
Background/Aim: This study was designed to provide further evidence for the interactions
between hydrogen sulfide (H2S) and nitric oxide (NO) in ischemia/reperfusion (I/R) injury …

Nitric oxide synthase inhibition abrogates hydrogen sulfide-induced cardioprotection in mice

B Sojitra, Y Bulani, UK Putcha, A Kanwal… - Molecular and cellular …, 2012 - Springer
The cardioprotective property of hydrogen sulfide (H 2 S) is recently reported. However,
cellular signaling cascades mediated by H 2 S are largely unclear. This study was …

[HTML][HTML] Dose-Dependent Effects of Long-Term Administration of Hydrogen Sulfide on Myocardial Ischemia–Reperfusion Injury in Male Wistar Rats: Modulation of …

S Jeddi, S Gheibi, K Kashfi, M Carlström… - International Journal of …, 2020 - mdpi.com
Decreased circulating levels of hydrogen sulfide (H2S) are associated with higher mortality
following myocardial ischemia. This study aimed at determining the long-term dose …

[HTML][HTML] Effect of hydrogen sulfide on inflammatory cytokines in acute myocardial ischemia injury in rats

F Liu, GJ Liu, N Liu, G Zhang… - Experimental and …, 2015 - spandidos-publications.com
Hydrogen sulfide (H2S) is believed to be involved in numerous physiological and
pathophysiological processes, and now it is recognized as the third endogenous signaling …

The protective role of hydrogen sulfide in myocardial ischemia–reperfusion-induced injury in diabetic rats

Y Gao, X Yao, Y Zhang, W Li, K Kang, L Sun… - International journal of …, 2011 - Elsevier
BACKGROUND: Hydrogen sulfide (H2S) displays anti-inflammatory and cytoprotective
activities to attenuate myocardial ischemia–reperfusion (MIR)-induced injury, but its role in …

Hydrogen sulfide and its possible roles in myocardial ischemia in experimental rats

YZ Zhu, ZJ Wang, P Ho, YY Loke… - Journal of Applied …, 2007 - journals.physiology.org
The role of hydrogen sulfide (H2S) in myocardial infarction (MI) has not been previously
studied. We therefore investigated the effect of H2S in a rat model of MI in vivo. Animals …

Cardioprotective effects of hydrogen sulfide

G Szabó, G Veres, T Radovits, D Gerő, K Módis… - Nitric Oxide, 2011 - Elsevier
The gaseous mediator hydrogen sulfide (H2S) is synthesized mainly by cystathionine γ-
lyase in the heart and plays a role in the regulation of cardiovascular homeostasis. Here we …

[HTML][HTML] Recent advances in the protective role of hydrogen sulfide in myocardial ischemia/reperfusion injury: a narrative review

ML Zhang, W Peng, JQ Ni, G Chen - Medical Gas Research, 2021 - journals.lww.com
Hydrogen sulfide (H 2 S) is recognized to be a novel mediator after carbon monoxide and
nitric oxide in the organism. It can be produced in various mammalian tissues and exert …

[HTML][HTML] Gaseous hydrogen sulfide protects against myocardial ischemia-reperfusion injury in mice partially independent from hypometabolism

PM Snijder, RA de Boer, EM Bos, JC van den Born… - PloS one, 2013 - journals.plos.org
Background Ischemia-reperfusion injury (IRI) is a major cause of cardiac damage following
various pathological processes. Gaseous hydrogen sulfide (H2S) is protective during IRI by …

Hydrogen sulfide mediates cardioprotection through Nrf2 signaling

JW Calvert, S Jha, S Gundewar, JW Elrod… - Circulation …, 2009 - Am Heart Assoc
Rationale: The recent emergence of hydrogen sulfide (H2S) as a potent cardioprotective
signaling molecule necessitates the elucidation of its cytoprotective mechanisms. Objective …