Cytotoxicity induced by docetaxel in human oral squamous cell carcinoma cell lines
S Iida, J Shimada, H Sakagami - in vivo, 2013 - iv.iiarjournals.org
Background: Comparative studies of cytotoxicity of docetaxel against both oral normal and
tumor cells are limited. In the present study, the cytotoxicity of docetaxel towards human oral …
tumor cells are limited. In the present study, the cytotoxicity of docetaxel towards human oral …
Lack of correlation between mitotic arrest or apoptosis and antitumor effect of docetaxel
R Schimming, KA Mason, N Hunter, M Weil… - Cancer chemotherapy …, 1999 - Springer
Purpose: To determine, as we did for paclitaxel, whether mitotic arrest and apoptosis
induced in murine tumors in vivo by docetaxel correlate with the drug's antitumor effect and …
induced in murine tumors in vivo by docetaxel correlate with the drug's antitumor effect and …
The growth inhibiting effect of docetaxel (TaxotereŽ) in head and neck squamous cell carcinoma xenografts
BJM Braakhuis, A Kegel, MJP Welters - Cancer letters, 1994 - Elsevier
Docetaxel (TaxotereŽ) is a new antitumor agent with activity in patients with ovarian, lung
and breast cancer. In this study, docetaxel was tested for its antitumor effect in human tumor …
and breast cancer. In this study, docetaxel was tested for its antitumor effect in human tumor …
An in vivo evaluation of docetaxel delivered intratumorally in head and neck squamous cell carcinoma
GH Yoo, G Subramanian, RR Boinpally… - … –Head & Neck …, 2005 - jamanetwork.com
Objective To identify activity and biological mechanisms of intratumoral (IT) docetaxel on
head and neck squamous cell carcinoma (HNSCC). Methods Docetaxel IT therapy was …
head and neck squamous cell carcinoma (HNSCC). Methods Docetaxel IT therapy was …
Docetaxel-induced apoptosis in melanoma cells is dependent on activation of caspase-2
Taxanes have a broad spectrum of activity against various human cancers, including
melanoma. In this study, we have examined the molecular mechanism of docetaxel-induced …
melanoma. In this study, we have examined the molecular mechanism of docetaxel-induced …
Docetaxel-induced apoptosis in the mitotic phase: electron microscopic and cytochemical studies of human leukemia cells
S Hagisawa, T Mikami, Y Sato - Medical Electron Microscopy, 1999 - Springer
We induced apoptosis in cells of the human leukemia cell line HL-60 using an antitumor
agent, docetaxel (Taxotere), and investigated apoptosis in various aspects using in situ end …
agent, docetaxel (Taxotere), and investigated apoptosis in various aspects using in situ end …
Novel hydrophilic docetaxel (CQMU‐0519) analogue inhibits proliferation and induces apoptosis in human A 549 lung, SKVO 3 ovarian and MCF 7 breast carcinoma …
NJS Fauzee, YL Wang, Z Dong, QG Li, T Wang… - Cell …, 2012 - Wiley Online Library
Objective Objectives of this investigation were not merely to perform a comparative study
with original docetaxel, but to define anti‐proliferative and apoptotic effects of novel …
with original docetaxel, but to define anti‐proliferative and apoptotic effects of novel …
The mechanism of action of docetaxel (TaxotereŽ) in xenograft models is not limited to bcl-2 phosphorylation
LA Kraus, SK Samuel, SM Schmid, DJ Dykes… - Investigational new …, 2003 - Springer
Docetaxel is a new taxoid compound with a broad spectrum of antitumor activity. Previous
studies have shown that in vitro treatment of specific human tumor lines with docetaxel is …
studies have shown that in vitro treatment of specific human tumor lines with docetaxel is …
Nanomolar range docetaxel treatment sensitizes MCF-7 cells to chemotherapy induced apoptosis, induces G2M arrest and phosphorylates bcl-2.
GJ Berchem, M Bosseler, N Mine, B Avalosse - Anticancer research, 1999 - europepmc.org
Docetaxel (Taxotere), a member of the taxoid family of chemotherapy drugs is currently
being tested in clinical trials simultaneously with other apoptosis inducing drugs like …
being tested in clinical trials simultaneously with other apoptosis inducing drugs like …
[HTML][HTML] γ-tocotrienol enhances the chemosensitivity of human oral cancer cells to docetaxel through the downregulation of the expression of NF-κB-regulated anti …
K Kani, Y Momota, M Harada… - International …, 2013 - spandidos-publications.com
Taxanes, including docetaxel, are widely used for the treatment of squamous cell carcinoma
of the head and neck. However, the gastrointestinal toxicity of docetaxel has limited its high …
of the head and neck. However, the gastrointestinal toxicity of docetaxel has limited its high …