Glucocorticoid receptor function suppresses insulin-like growth factor 1 activity in human KLE endometrial-like cells

P Lembessis, N Kalariti, M Koutsilieris - in vivo, 2004 - iv.iiarjournals.org
We analysed the glucocorticoid receptor (GR) regulation on the expression of insulin-like
growth factor 1 (IGF-1), type I IGF receptor (IGF-1. R), IGF-binding protein 3 (IGFBP-3) …

The glucocorticoid receptor is specifically expressed in the stromal compartment of the human endometrium

AM Bamberger, K Milde-Langosch… - The Journal of …, 2001 - academic.oup.com
The human endometrium is a classical target tissue for steroid hormones. While the
expression pattern and functional roles of both the estrogen receptor (ER) and the …

Steroid-modulated proliferation of human endometrial carcinoma cell lines: any role for insulin-like growth factor signaling?

SCJP Gielen, EE Hanekamp, LJ Blok… - Journal of the …, 2005 - journals.sagepub.com
Objectives: Estrogen-stimulated proliferation of the normal and malignant human
endometrium is balanced by the differentiating properties ofprogesterone. This study …

Estradiol, progesterone, and transforming growth factor α regulate insulin-like growth factor binding protein-3 (IGFBP3) expression in mouse endometrial cells

T Maekawa, S Takeuchi, M Kanayama, S Takahashi - Zoological science, 2009 - BioOne
Insulin-like growth factor 1 (IGF1) is involved in the proliferation of mouse and rat
endometrial cells in a paracrine or autocrine manner. Insulin-like growth factor binding …

Characterization of the steroid-dependence of insulin-like growth factor-binding protein-2 synthesis and mRNA expression in cultured human endometrial stromal …

LC Giudice, DA Milkowski, PJ Fielder… - Human …, 1991 - academic.oup.com
The insulin-like growth factors (IGF-I and-II) are believed to be important in endometrial
differentiation and blastocyst nidation, and proteins that regulate IGF action (IGF-binding …

Insulin-like growth factor regulation of human endometrial stromal cell function: coordinate effects on insulin-like growth factor binding protein-1, cell proliferation and …

JC Irwin, L de las Fuentes, BA Dsupin, LC Giudice - Regulatory peptides, 1993 - Elsevier
The insulin-like growth factor (IGF) autocrine/paracrine system is believed to be involved in
endometrial differentiation, but there is limited information on the specific cellular functions …

Steroid and peptide regulation of insulin-like growth factor-binding proteins secreted by human endometrial stromal cells is dependent on stromal differentiation

LC Giudice, BA Dsupin, JC Irwin - The Journal of Clinical …, 1992 - academic.oup.com
Endometrial stromal cells undergo decidual transformation, in response to epidermal growth
factor (EGF) and progesterone. Since insulin-like growth factors (IGFs) and IGF-binding …

Are growth factor receptors modulated by metformin in human endometrial stromal cells after stimulation with androgen and insulin?

GD Ferreira, A Germeyer, A de Barros Machado… - Archives of gynecology …, 2014 - Springer
Objective To assess the effect of metformin on gene and protein expression of insulin
receptor (IR) and IGF-1 (IGF-1R) receptor in human endometrial stromal cells after …

GnRH II as a possible cytostatic regulator in the development of endometriosis

C Morimoto, Y Osuga, T Yano, Y Takemura… - Human …, 2005 - academic.oup.com
BACKGROUND: GnRH II is the second form of GnRH and is widely distributed in peripheral
tissues of the female reproductive tract as well as in the central nervous system. In the …

[HTML][HTML] Insulinlike Growth Factor-1Ec (MGF) Expression in Eutopic and Ectopic Endometrium: Characterization of the MGF E-Peptide Actions In Vitro

DS Milingos, A Philippou, A Armakolas… - Molecular …, 2011 - Springer
The transcription of the insulinlike growth factor 1 (igf-1) gene generates three mRNA
isoforms, namely IGF-1Ea, IGF-1Eb and IGF-1Ec (or MGF [mechano growth factor]). Herein …