Coagulation activity and white thrombus formation in the microminipig

N Miura, H Kawaguchi, T Nagasato, T Yamada, T Ito… - In Vivo, 2013 - iv.iiarjournals.org
Swine are becoming increasingly attractive as animal models for clinical research and the
recently developed Microminipig (MMPig) has emerged as a possible experimental animal …

Reference values of biochemical and hematological parameters for Guizhou minipigs

Y Chen, S Qin, Y Ding, S Li, G Yang… - Experimental …, 2011 - journals.sagepub.com
The pig is not only an economically important livestock animal but is also a valuable model
animal for biomedical research and xenotransplantation. Reference values for clinical …

The pig as a model in blood coagulation and fibrinolysis research

AK Olsen, AK Hansen, J Jespersen… - … Journal of Laboratory …, 1999 - ojs.utlib.ee
The pig as a model in blood coagulation and Page 1 Scand. J. Lab Anim. Sci. No, 4, 1999 Vol.
26 The pig as a model in blood coagulation and fibrinolysis research by Aage Kristian Olsen"*" …

Reference values of hematological and biochemical parameters for the world smallest microminipigs

H Kawaguchi, T Yamada, N Miura… - Journal of Veterinary …, 2012 - jstage.jst.go.jp
In this study, we demonstrated growth curves and reference values for hematological and
serum biochemical parameters of Microminipigs, the world smallest experimental minipigs …

In vitro evaluation of blood coagulation activation and microthrombus formation by a microchannel array flow analyzer

H Kamada, K Hattori, T Hayashi, K Suzuki - Thrombosis research, 2004 - Elsevier
An in vitro assay system for evaluating microthrombus formation in whole blood has not yet
been established. In this study, we characterized the relationship between coagulation …

The Aachen minipig: phenotype, genotype, hematological and biochemical characterization, and comparison to the Göttingen minipig

K Pawlowsky, L Ernst, J Steitz, T Stopinski… - European Surgical …, 2017 - karger.com
Background: The pig is one of the most frequently used large animal models for biomedical
research, especially in the field of translational research and surgical models. While …

[HTML][HTML] A novel microchip flow chamber (Total Thrombus Analysis System) to assess canine hemostasis

T Iwanaga, N Miura, BM Brainard… - Frontiers in Veterinary …, 2020 - frontiersin.org
Hemorrhagic diseases are common in dogs. Current coagulation assays do not model all
aspects of in vivo hemostasis and may not predict bleeding risk. The Total-Thrombus …

Interspecies differences in coagulation profile

JM Siller-Matula, R Plasenzotti, A Spiel… - Thrombosis and …, 2008 - thieme-connect.com
Many animals are used in research on blood coagulation and fibrinolysis, but the relevance
of animal models to human health is often questioned because of differences between …

Sex differences of serum lipid profile in novel microminipigs

H Kawaguchi, T Yamada, N Miura, M Noguchi, H Izumi… - In Vivo, 2013 - iv.iiarjournals.org
Swine have been used extensively in biomedical research, with a significant increase in
recent decades. Minipigs are increasingly becoming an especially attractive animal model in …

Analysis of blood clotting with the total thrombus analysis system in healthy dogs

T Iwanaga, R Fukushima, T Nagasato… - Journal of …, 2021 - journals.sagepub.com
To date, coagulation tests are unable to reflect in vivo coagulation status in the same system,
including platelet function, fibrin clot formation, and whole blood flow. The Total Thrombus …