Background: Although numerous articles have dealt with the biological activities of
azulenes, studies of benzo [b] cyclohept [e][1, 4] oxazines are limited. In the present study …

A total of twenty benzo [b] cyclohept [e][1, 4] oxazines and their S-analogs, and 2-
aminotropone derivatives were investigated for their cytotoxicity against three human normal …

Twenty-six benzocycloheptoxazine derivatives were investigated for their tumor-specific
cytotoxicity and apoptosis-inducing activity against three human normal cells (gingival …

Tumor-specificity (TS) and anti-inflammatory activity of benzo [b] cyclohept [e][1, 4] oxazin-6
(11H)-one, generally known as benzoxazinotropone (BOT), have been reported. In order to …

Oxazine derivatives, a class of heterocyclic compounds, exhibit a variety of biological
properties, such as anticonvulsant and antitumor activities. In this study, we evaluated the …

Background/Aim: There exist few research articles regarding the anticancer activity of
azulene-related compounds. We investigated here the relative cytotoxicity of 10 azulene …

We describe the synthesis of previously unknown halogenated derivatives of 2-(benzo [b][1,
4] oxazepino [7, 6, 5-de] quinolin-2-yl)-1, 3-tropolone. The MTT colorimetric assay was used …

Background: The genetic heterogeneity of tumor cells and the development of therapy-
resistant cancer cells in addition to the high cost necessitate the continuous development of …

The aim of the present study is to synthesize new benzoxazine and aminomethyl derivatives
of eugenol, and to examine the cytotoxicity of the derivatives on MCF-7 cells. 6-Alyl-3-(4 …

We investigated twenty-seven azulenequinone derivatives for their relative cytotoxicity
against three human normal cell lines (HGF, HPC, HPLF) and four human tumor cell lines …