Making ICSI safer and more effective: a review of the human oocyte and ICSI practice

M Simopoulou, P Giannelou, P Bakas, L Gkoles… - in vivo, 2016 - iv.iiarjournals.org
Intracytoplasmic sperm injection (ICSI) has become an indispensable procedure of every
assisted reproduction unit. This has created as much controversy as it has awe. As this is a …

Impact of intracytoplasmic sperm injection on the activation and fertilization process of oocytes

M Ludwig, AK Schröder, K Diedrich - Reproductive BioMedicine Online, 2001 - Elsevier
Intracytoplasmic sperm injection (ICSI) is used worldwide to treat preferentially severe cases
of male factor infertility. In this review, data regarding the processes of oocyte activation and …

The ICSI procedure from past to future: a systematic review of the more controversial aspects

P Rubino, P Viganò, A Luddi… - Human reproduction …, 2016 - academic.oup.com
BACKGROUND ICSI is currently the most commonly used assisted reproductive technology,
accounting for 70–80% of the cycles performed. This extensive use, even excessive, is partly …

ICSI: where we have been and where we are going

GD Palermo, QV Neri, T Takeuchi… - Seminars in …, 2009 - thieme-connect.com
Notwithstanding the broad success of in vitro fertilization (IVF), a failure to achieve
fertilization still plagues a substantial group of patients, with sperm abnormalities the main …

Current and future perspectives on intracytoplasmic sperm injection: a critical commentary

AC Varghese, E Goldberg, A Agarwal - Reproductive BioMedicine Online, 2007 - Elsevier
Intracytoplasmic sperm injection (ICSI) is an increasingly popular means of treating infertility
in couples who wish to conceive. However, there are many potential complications that can …

Strategies to improve fertilisation rates with assisted conception: a systematic review

YB Jeve, N Potdar, JA Blower, T Gelbaya - Human Fertility, 2018 - Taylor & Francis
Successful fertilisation is one of the key steps determining success of assisted conception.
Various factors including sperm or oocyte pathology and environmental factors have a …

ICSI: hype or hazard?

W Verpoest, H Tournaye - Human fertility, 2006 - Taylor & Francis
Ever since its introduction in clinical practice more than 10 years ago, intracytoplasmic
sperm injection (ICSI) has been the subject of ongoing debate regarding its indications and …

New advances in intracytoplasmic sperm injection (ICSI)

L Parmegiani, GE Cognigni… - Advances in embryo …, 2012 - books.google.com
In these last twenty years, intracytoplasmic sperm injection (ICSI) has efficiently permitted
the treatment of male factor infertility (Van Steirteghem et al., 1993); the direct injection of …

Impact of oocyte pre-incubation time on fertilization, embryo quality and pregnancy rate after intracytoplasmic sperm injection

A Isiklar, R Mercan, B Balaban, C Alatas… - Reproductive …, 2004 - Elsevier
Although, it is well known that pre-incubation of oocytes prior to conventional IVF improves
fertilization and pregnancy rates, there are conflicting results regarding the effect of pre …

Intracytoplasmic sperm injection indications: how rigorous?

SN Babayev, CW Park… - Seminars in reproductive …, 2014 - thieme-connect.com
Up to 15% of all couples of reproductive age are diagnosed with subfertility and about one-
third of those will have male factor infertility as a contributing factor. Intracytoplasmic sperm …