Vanillin enhances TRAIL-induced apoptosis in cancer cells through inhibition of NF-κB activation

K Lirdprapamongkol, H Sakurai, S Suzuki, K Koizumi… - in vivo, 2010 - iv.iiarjournals.org
Background: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising
anticancer agent which selectively kills cancer cells with little effect on normal cells …

[HTML][HTML] Juglone potentiates TRAIL‑induced apoptosis in human melanoma cells via activating the ROS‑p38‑p53 pathway

X Liu, Y Chen, Y Zhang, J Du, Y Lv… - Molecular …, 2017 - spandidos-publications.com
Tumor necrosis factor‑related apoptosis‑inducing ligand (TRAIL)‑based cancer therapy
offers promise as TRAIL can kill cancer cells without apparent toxicity towards normal cells …

Kaempferol improves TRAIL-mediated apoptosis in leukemia MOLT-4 cells by the inhibition of anti-apoptotic proteins and promotion of death receptors expression

A Hassanzadeh, A Naimi, MF Hagh… - Anti-Cancer Agents …, 2019 - ingentaconnect.com
Introduction: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL or Apo2L) is a
member of the Tumor Necrosis Factor (TNF) superfamily, which stimulates apoptosis in a …

[HTML][HTML] Dietary flavonoids sensitize HeLa cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)

E Szliszka, ZP Czuba, K Jernas, W Król - International Journal of …, 2008 - mdpi.com
TRAIL is a promising candidate for cancer therapeutics that preferentially induces apoptosis
in cancer cells. The combined treatment flavonoids with TRAIL might be promising as a …

[HTML][HTML] Synthetic flavanones augment the anticancer effect of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)

E Szliszka, E Kostrzewa-Susłow, J Bronikowska… - Molecules, 2012 - mdpi.com
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is considered as the most
promising anticancer agent in the TNF superfamily because of its selective cytotoxicity …

[HTML][HTML] Baicalin potentiates TRAIL‑induced apoptosis through p38 MAPK activation and intracellular reactive oxygen species production

L Zhang, X Wang, R Wang… - Molecular …, 2017 - spandidos-publications.com
The combination of tumor necrosis factor‑related apoptosis‑inducing ligand (TRAIL) with
other agents has been recognized as a promising strategy to overcome TRAIL resistance in …

[HTML][HTML] Shikonin sensitizes A549 cells to TRAIL-induced apoptosis through the JNK, STAT3 and AKT pathways

ZL Guo, JZ Li, YY Ma, D Qian, JY Zhong, MM Jin… - BMC cell biology, 2018 - Springer
Background TRAIL, tumor necrosis factor-related apoptosis-inducing ligand, can selectively
kill cancer cells with little or no cytotoxicity toward normal human cells and is regarded as a …

TRAIL apoptosis is enhanced by quercetin through Akt dephosphorylation

YH Kim, YJ Lee - Journal of cellular biochemistry, 2007 - Wiley Online Library
TNF‐related apoptosis‐inducing ligand (TRAIL) is a promising cancer therapy that
preferentially induces apoptosis in cancer cells. However, many neoplasms are resistant to …

[HTML][HTML] TRAIL-sensitizing effects of flavonoids in cancer

A Luiz-Ferreira, T Pacifico, ÁC Cruz, F Laudisi… - International Journal of …, 2023 - mdpi.com
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) represents a promising
anticancer agent, as it selectively induces apoptosis in transformed cells without altering the …

Luteolin sensitizes human 786-O renal cell carcinoma cells to TRAIL-induced apoptosis

YC Ou, JR Li, YH Kuan, SL Raung, CC Wang, YY Hung… - Life sciences, 2014 - Elsevier
Aims Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has been considered
to be one of the most promising candidates in research on treatments for cancer, including …