Predictive value of osteoprotegerin and neutrophil gelatinase-associated lipocalin on multiple organ failure in multiple trauma

H Peters, C Macke, P Mommsen, C Zeckey… - in vivo, 2019 - iv.iiarjournals.org
Background/Aim: Multiple organ dysfunction syndrome (MODS) is the leading cause of late
posttraumatic mortality. This study analyzed the prognostic values of osteoprotegerin (OPG) …

[HTML][HTML] Neutrophil gelatinase-associated lipocalin as a biomarker for short-term outcomes among trauma patients: a single-center observational study

S Minami, T Doi, T Abe, I Takeuchi - Plos one, 2021 - journals.plos.org
Background Urinary biomarkers for organ dysfunction could predict the outcomes of severe
trauma patients. However, the use of neutrophil gelatinase-associated lipocalin (NGAL) as a …

Early increase in anti-inflammatory biomarkers is associated with the development of multiple organ dysfunction syndrome in severely injured trauma patients

DJB Kleinveld, AM Tuip-de Boer… - Trauma Surgery & …, 2019 - tsaco.bmj.com
Background As a result of improvements in the early resuscitation phase of trauma, mortality
is largely driven by later mortality due to multiple organ dysfunction syndrome (MODS) …

Neutrophil‐to‐lymphocyte ratio in relation to trauma severity as prognosis factors in patients with multiple injuries complicated by multiple organ dysfunction syndrome …

YM He, X Liu, SY Zhong, QH Fu - Immunity, Inflammation and …, 2023 - Wiley Online Library
Objective This study aimed to explore potential risk factors for the occurrence of multiple
organ dysfunction syndrome (MODS) in patients with multiple injuries by evaluating …

Neutrophil gelatinase-associated lipocalin predicts post-traumatic acute kidney injury in severely injured patients

K Leditzke, MEH Wagner, C Neunaber, JD Clausen… - in vivo, 2021 - iv.iiarjournals.org
Background: Early detection of acute kidney injury (AKI) is crucial in the management of
multiple-organ dysfunction syndrome in severely injured patients. Standard laboratory …

[HTML][HTML] Diagnostic utility of serum neutrophil gelatinase-associated lipocalin in polytraumatized patients suffering acute kidney injury: a prospective study

LL Negrin, R Hahn, T Heinz, S Hajdu - BioMed research …, 2018 - hindawi.com
Introduction. The incidence of acute kidney injury (AKI) considerably increases the mortality
rate in polytrauma victims. Undoubtedly, early identification of patients at risk is crucial for …

Elevated systemic IL-18 and neopterin levels are associated with posttraumatic complications among patients with multiple injuries: a prospective cohort study

P Mommsen, M Frink, HC Pape, M Van Griensven… - Injury, 2009 - Elsevier
INTRODUCTION: Posttraumatic systemic inflammatory response syndrome (SIRS), sepsis
and their subsequent complication, the multiple-organ dysfunction syndrome (MODS) …

[HTML][HTML] Pattern of cytokine (IL-6 and IL-10) level as inflammation and anti-inflammation mediator of multiple organ dysfunction syndrome (MODS) in polytrauma

HB Sapan, I Paturusi, I Jusuf, I Patellongi… - … journal of burns and …, 2016 - ncbi.nlm.nih.gov
Massive injury remains the most common cause of death for productive age group globally.
The current immune, inflammatory paradigm, based on an incomplete understanding of the …

Serum neutrophil gelatinase–associated lipocalin in ballistic injuries: A comparison between blast injuries and gunshot wounds

AJ Mellor, D Woods - Journal of critical care, 2012 - Elsevier
Neutrophil gelatinase–associated lipocalin (NGAL) is part of a functionally diverse family of
proteins that generally bind small, hydrophobic ligands. Neutrophil gelatinase–associated …

[HTML][HTML] Multiple organ dysfunction syndrome (MODS) prediction score in multi-trauma patients

L Rendy, HB Sapan, LTB Kalesaran - International Journal of Surgery Open, 2017 - Elsevier
Background Multiple organ dysfunction syndrome (MODS) in patients with major trauma
remains a frequent and devastating complication in emergency departments and intensive …