Gain of an isochromosome 5p: a rare recurrent abnormality in acute myeloid leukemia

AD Panani - in vivo, 2006 - iv.iiarjournals.org
Chromosomal abnormalities characterize the biological behavior of acute myeloid leukemia
(AML), also facilitating the identification of genes responsible for its development and/or …

Gain of an isochromosome 5p:: a new recurrent chromosome abnormality in acute monoblastic leukemia

C Schoch, S Bursch, W Kern, S Schnittger… - Cancer genetics and …, 2001 - Elsevier
In acute myeloid leukemia (AML) close associations are known between cytomorphology
and cytogenetics such as in AML M3/M3v showing at (15; 17) and in AML M4eo associated …

Double Inv (3)(q21q26), a rare but recurrent chromosomal abnormality in myeloid hemopathies

E De Braekeleer, N Douet-Guilbert… - Anticancer …, 2013 - ar.iiarjournals.org
Inv (3)(q21q26)/t (3; 3)(q21; q26) is a feature of a distinctive entity of acute myeloid leukemia
(AML) associated with normal or elevated platelet count, atypical megakaryocytes and …

Tetrasomy 13 as the sole cytogenetic abnormality in acute myeloid leukemia M1 without maturation

P McGrattan, HD Alexander, MW Humphreys… - Cancer genetics and …, 2002 - Elsevier
We report a case of acute myeloid leukemia (AML) M1 showing a 48, XY,+ 13,+ 13
karyotype. Treatment was according to the Medical Research Council AML14 trial protocol …

Isodicentric 7p, idic (7)(q11. 2), in acute myeloid leukemia associated with older age and favorable response to induction chemotherapy: A new clinical entity?

B Johansson, P Axelsson, R Billström… - Genes …, 2001 - Wiley Online Library
Three adult de novo acute myeloid leukemias (AML M1, M2, and M4) with an
isochromosome 7p are presented. No additional abnormalities were detected by G‐band …

Partial deletion of chromosome 1 in a case of acute myelocytic leukemia

LA Coupland, V Jammu, ME Pidcock - Cancer genetics and cytogenetics, 2002 - Elsevier
Acute myelocytic leukemia (AML) is a malignant disease characterized by the proliferation of
immature myelocytic precursor cells causing the disruption of normal bone marrow function …

Karyotypically independent clones with del (11q) and trisomy 10 in acute myeloid leukemia: trisomy 10 may appear as an additional change

M Gotoh, Y Sasaki, T Iguchi, H Fujimoto… - International journal of …, 2008 - Springer
At the genomic level, acute myeloid leukemia (AML) is characterized by translocations,
inversions and/or deletions involving certain key gene segments, with disruption of the …

Deletions of chromosome arms 7p and 7q in adult acute myeloid leukemia: a marker chromosome confirmed by array comparative genomic hybridization

KS Woo, KE Kim, KH Kim, SH Kim, JI Park… - Cancer genetics and …, 2009 - Elsevier
Acute myeloid leukemia (AML) cases with monosomy 7 (− 7) and del (7q) comprise a
heterogeneous subgroup. The association of losses in 7q with myeloid leukemia suggests …

del(6)(p23) in two cases of de novo AML – a new recurrent primary chromosome abnormality

M Anwar Iqbal, HM Al‐Omar, T Owaidah… - European journal of …, 2006 - Wiley Online Library
Objective: Previously, deletion 6p23 was generally reported in therapy‐related secondary
acute myeloid leukemia (AML) as part of complex karyotypes. In this report, we present two …

Association of 3q21q26 syndrome and late-appearing Philadelphia chromosome in acute myeloid leukemia

A Quintás-Cardama, DL Gibbons, J Cortes, D Bobadilla… - Leukemia, 2008 - nature.com
Structural abnormalities in the long arm of chromosome 3 have been detected in 7–10% of
patients with acute myelogenous leukemia (AML) or myelodysplastic syndromes. Patients …