Apoptosis and cell proliferation correlated with tumor grade in patients with lung adenocarcinoma

A Kalogeraki, M Tzardi, O Zoras, E Giannikaki… - in vivo, 2010 - iv.iiarjournals.org
Background: Apoptosis and cell proliferation in patients with adenocarcinoma of the lung
have not been well described with relation to fine-needle aspiration biopsies (FNABs). To …

Imbalance of cell proliferation and apoptosis during progression of lung carcinomas

J Mattern, M Volm - Anticancer research, 2004 - ar.iiarjournals.org
To evaluate the relationship between cell proliferation and apoptosis during progression of
lung carcinomas, immunohistochemistry for proliferating cell nuclear antigen (PCNA) and …

Evidence for apoptosis in non-small cell lung carcinoma. Relationship with cell kinetics and prognosis.

L Matturri, B Colombo, AM Lavezzi - Analytical and quantitative …, 1999 - europepmc.org
Objective To investigate cell death via apoptosis in non-small cell lung carcinoma (NSCLC)
and its correlation with proliferative indices and follow-up. Study design In 38 cases of …

Cell loss and proliferation in non-small cell lung carcinoma: correlation with histological subtype.

F Mangili, C Cigala, G Arrigoni, E Rovere… - European journal of …, 1998 - europepmc.org
Background Cell kinetic data are important indicators of the aggressiveness of tumor and
treatment response. The size of a neoplasm depends on the balance between cell …

Balance between cell division and cell death as predictor of survival in patients with non-small-cell lung cancer

F Puglisi, AM Minisini, G Aprile, F Barbone, P Cataldi… - Oncology, 2002 - karger.com
Objective: To evaluate the prognostic value of the balance between apoptosis and
proliferation in non-small-cell lung cancer (NSCLC). Methods: Paraffin-embedded sections …

Prognostic value of the apoptotic index analysed jointly with selected cell cycle regulators and proliferation markers in non-small cell lung cancer

D Dworakowska, E Jassem, J Jassem, A Karmoliński… - Lung Cancer, 2009 - Elsevier
In a previous small series of surgically treated non-small cell lung cancer patients (NSCLC),
we found that higher apoptotic index (AI) negatively influenced survival (Dworakowska D …

Apoptosis in non-small cell lung cancer as related to drug resistance and prognosis

G Stammler, M Volm - Apoptosis, 1996 - Springer
The percentage of apoptotic cells among the tumor cells (apoptotic index) was determined in
a series of 178 non-small cell lung carcinomas with a long term clinical follow-up by a …

Enhanced apoptosis predicts shortened survival in non-small cell lung carcinoma

U Törmänen, AK Eerola, P Rainio, K Vähäkangas… - Cancer research, 1995 - AACR
This study was undertaken to determine the extent of apoptosis in lung carcinoma and to
evaluate it as a prognostic marker. A series of 75 lung carcinomas (47 squamous cell …

Clinical significance of apoptotic index in non-small cell lung cancer: correlation with p53, mdm2, pRb and p21WAF1/CIP1 protein expression

D Dworakowska, E Jassem, J Jassem… - Journal of cancer …, 2005 - Springer
Purpose: The aim of this study was to assess the prognostic relevance of apoptotic index
(AI), considered alone or together with expression of several proteins controlling G1 check …

Apoptosis in squamous cell carcinoma of the lung: correlation with survival and clinicopathological features

M Ghosh, J Crocker, A Morris - Journal of clinical pathology, 2001 - jcp.bmj.com
Aims—Apoptosis is recognised as a physiological mechanism for controlling cell numbers
and its subversion is thought to contribute to carcinogenesis. The aims of this study were to …