Preclinical models for drug discovery for metastatic disease
Despite many advances, metastatic disease remains essentially uncurable. Thus, there is an
urgent need to better understand mechanisms that promote metastasis, drive tumor …
urgent need to better understand mechanisms that promote metastasis, drive tumor …
[HTML][HTML] Cell lines of circulating tumor cells: what is known and what needs to be resolved
Y Shimada, T Sudo, S Akamatsu, T Sunada… - Journal of Personalized …, 2022 - mdpi.com
The importance of circulating tumor cells (CTC) is well recognized. However, the biological
characteristics of CTC in the bloodstream have not yet been examined in detail, due to the …
characteristics of CTC in the bloodstream have not yet been examined in detail, due to the …
[HTML][HTML] Conditionally reprogrammed cells and robotic high-throughput screening for precision cancer therapy
F Alkhilaiwi - Frontiers in Oncology, 2021 - frontiersin.org
Cancer is a devastating disease that takes the lives of millions of people globally every year.
Precision cancer therapy is based on a patient's tumor histopathology, expression analyses …
Precision cancer therapy is based on a patient's tumor histopathology, expression analyses …
State of the Art in the Propagation of Circulating Tumor Cells
Circulating tumor cells (CTCs) are a group of cells that travel through the circulatory system
of a cancer patient, sowing distant sites and forming the seeds for metastatic nodules. Given …
of a cancer patient, sowing distant sites and forming the seeds for metastatic nodules. Given …
[BOOK][B] Investigating the Mechanisms of Cancer Metastasis Through Novel in Vitro and in Vivo Models
J Xiao - 2022 - search.proquest.com
Cancer is the second highest cause of death globally. In an estimated 90% of all cases, the
spread of cancer cells from the initial tumor to a distant site—aka metastasis—is the primary …
spread of cancer cells from the initial tumor to a distant site—aka metastasis—is the primary …
Clinical significance of circulating tumor cells testing in auxiliary diagnosis ofgastrointestinal cancer
W Zhaoxia, Z Lei - Indian Journal of Experimental Biology (IJEB), 2022 - or.niscpr.res.in
Routine diagnostic tools and serum biomarkers of gastrointestinal (GI) cancer has limits in
detecting early and micrometastasis, and circulating tumor cells (CTCs) had emerged as a …
detecting early and micrometastasis, and circulating tumor cells (CTCs) had emerged as a …
[HTML][HTML] Detection of Circulating Tumor Cells Using Three-dimensional and Conditionally Reprogrammed Culture Methods
C Park, YJ Jeong, SH Park, DD Kim… - Laboratory Medicine … - synapse.koreamed.org
Background Circulating tumor cells (CTCs) are rare in the circulation of patients with tumors
and are very difficult to detect. In this study, we cultured CTCs in a three-dimensionally …
and are very difficult to detect. In this study, we cultured CTCs in a three-dimensionally …