[HTML][HTML] Genetic polymorphisms associated with susceptibility to COVID-19 disease and severity: A systematic review and meta-analysis

C Dieter, LA Brondani, CB Leitão, F Gerchman… - PLoS …, 2022 - journals.plos.org
Although advanced age and presence of comorbidities significantly impact the variation
observed in the clinical symptoms of COVID-19, it has been suggested that genetic variants …

[HTML][HTML] Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics

Y Gupta, OV Savytskyi, M Coban, A Venugopal… - Molecular Aspects of …, 2023 - Elsevier
With more than 5 million fatalities and close to 300 million reported cases, COVID-19 is the
first documented pandemic due to a coronavirus that continues to be a major health …

Drugs that offer the potential to reduce hospitalization and mortality from SARS-CoV-2 infection: The possible role of the sigma-1 receptor and autophagy

JM Brimson, MI Prasanth, DS Malar… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction: Despite the availability of new vaccines for SARS-CoV-2, there has been slow
uptake and problems with supply in some parts of the world. Hence, there is still a necessity …

[HTML][HTML] A conformational rearrangement of the SARS-CoV-2 host protein sigma-1 is required for antiviral activity: insights from a combined in-silico/in-vitro approach

FS Abatematteo, P Delre, I Mercurio, VV Rezelj… - Scientific Reports, 2023 - nature.com
The development of effective drugs to treat coronavirus infections remains a significant
challenge for the scientific community. Recent evidence reports on the sigma-1 receptor …

[HTML][HTML] Neuropsychiatric drugs against COVID-19: What is the clinical evidence?

JK Mueller, P Riederer, WE Müller - Pharmacopsychiatry, 2022 - thieme-connect.com
Since the beginning of the coronavirus disease (COVID)-19 pandemic, the need for effective
treatments for COVID-19 led to the idea of “repurposing” drugs for antiviral treatment …

Genetics of COVID‐19 and myalgic encephalomyelitis/chronic fatigue syndrome: a systematic review

M Tziastoudi, C Cholevas, I Stefanidis… - Annals of Clinical …, 2022 - Wiley Online Library
Abstract COVID‐19 and ME/CFS present with some similar symptoms, especially physical
and mental fatigue. In order to understand the basis of these similarities and the possibility of …

[HTML][HTML] Effects of selected inherited factors on susceptibility to SARS-CoV-2 infection and COVID-19 progression

JA Hubacek - Physiological Research, 2021 - ncbi.nlm.nih.gov
Genetic predispositions may influence geographical and interethnic differences in COVID-
19 prevalence and mortality in affected populations. Of the many genes implicated in COVID …

[HTML][HTML] Cross-national variations in COVID-19 mortality: the role of diet, obesity and depression

RP Rajkumar - Diseases, 2021 - mdpi.com
Background: The COVID-19 pandemic has been characterized by wide variations in
mortality across nations. Some of this variability may be explained by medical comorbidities …

[HTML][HTML] Molecular bases of serotonin reuptake inhibitor antidepressant-attributed effects in COVID-19: A new insight on the role of bradykinins

AS Gouda, B Mégarbane - Journal of Personalized Medicine, 2022 - mdpi.com
Widely available effective drugs to treat coronavirus disease-2019 (COVID-19) are still
limited. Various studies suggested the potential contribution of selective serotonin-reuptake …

[PDF][PDF] Psychopharmaka: Therapeutische Perspektiven gegen Covid-19

JK Müller, WE Müller - Psychopharmakotherapie, 2021 - ppt-online.de
Bedingt durch den großen Zeitdruck bei der Suche nach neuen Medikamenten gegen Covid-
19 hat man in der letzten Zeit vermehrt versucht, wirksame Substanzen unter bereits in …