[HTML][HTML] FGF23 and associated disorders of phosphate wasting

A Gohil, EA Imel - Pediatric endocrinology reviews: PER, 2019 - ncbi.nlm.nih.gov
Abstract Fibroblast growth factor 23 (FGF23), one of the endocrine fibroblast growth factors,
is a principal regulator in the maintenance of serum phosphorus concentration. Binding to its …

[HTML][HTML] Rickets in children: an update

C Gentile, F Chiarelli - Biomedicines, 2021 - mdpi.com
Rickets refers to a deficient mineralization of the growth plate cartilage, predominantly
affecting longer bones. Despite the fact that preventive measures are available, it is still a …

[HTML][HTML] Predicting biomedical relationships using the knowledge and graph embedding cascade model

X Liang, D Li, M Song, A Madden, Y Ding, Y Bu - PLoS One, 2019 - journals.plos.org
Advances in machine learning and deep learning methods, together with the increasing
availability of large-scale pharmacological, genomic, and chemical datasets, have created …

FGF23 and the PTH response to paricalcitol in chronic kidney disease

G D'Arrigo, P Pizzini, S Cutrupi… - European Journal of …, 2020 - Wiley Online Library
Background The parathyroid glands are endowed both with receptors responsive to FGF23
and to 1, 25 vitamin D. Vitamin D receptor (VDR) activation, besides lowering PTH, also …

[HTML][HTML] The efficacy and safety of different doses of calcitriol combined with neutral phosphate in X-linked hypophosphatemia: a prospective study

C Jin, C Zhang, X Ni, Z Zhao, L Xu, B Wu, Y Chi… - Osteoporosis …, 2022 - Springer
The present study was the first prospective cohort evaluated the efficacy and safety of
different doses of calcitriol in XLH children. The results suggested that a dose of 40 …

[HTML][HTML] Association of anabolic effect of calcitriol with osteoclast-derived wnt 10b secretion

CL Lu, JF Shyu, CC Wu, CF Hung, MT Liao, WC Liu… - Nutrients, 2018 - mdpi.com
Canonical Wnt (Wingless/Integrated) signaling is crucial in bone development and the Wnt
ligand can promote osteoblast differentiation from mesenchymal progenitor cells. Calcitriol …

[HTML][HTML] Effect of salt intervention on serum levels of fibroblast growth factor 23 (FGF23) in Chinese adults: an intervention study

JW Hu, Y Wang, C Chu, JJ Mu - Medical science monitor …, 2018 - ncbi.nlm.nih.gov
Background Fibroblast growth factor 23 (FGF23), a prominent regulator of phosphate and
calcium metabolism, regulates sodium excretion in distal tubules through sodium-chloride …

Nephropathic cystinosis: a distinct form of CKD–mineral and bone disorder that provides novel insights into the regulation of FGF23

P Florenzano, M Jimenez, CR Ferreira… - Journal of the …, 2020 - journals.lww.com
Background The rare lysosomal storage disease nephropathic cystinosis presents with renal
Fanconi syndrome that evolves in time to CKD. Although biochemical abnormalities in …

The effect of vitamin D supplementation on serum levels of fibroblast growth factor-23: A systematic review and meta-analysis of randomized controlled trials

F Meshkini, S Soltani, CCT Clark, V Tam… - The Journal of steroid …, 2022 - Elsevier
Previous studies of the effect of vtamin D on serum levels of fibroblast growth factor-23 (FGF-
23) have yeilded an inconsistent findings. This systematic review and meta-analysis of …

[HTML][HTML] Reduced phosphorus intake throughout gestation and lactation of sows is mitigated by transcriptional adaptations in kidney and intestine

A Wubuli, C Gerlinger, H Reyer, M Oster, E Muráni… - BMC genomics, 2020 - Springer
Background The environmental impact of pig farming need to be reduced, with phosphorus
(P) being of particular interest. Specified dietary regimens and management systems …