The potential health benefits of the isoflavone glycoside genistin

A Islam, MS Islam, MN Uddin, MMI Hasan… - Archives of pharmacal …, 2020 - Springer
Genistin is a type of isoflavone glycoside and has a broad range of health benefits. It is
found in a variety of dietary plants, such as soybean, kudzu (Japanese arrowroot), and other …

Notoginsenoside R1-mediated neuroprotection involves estrogen receptor-dependent crosstalk between Akt and ERK1/2 pathways: a novel mechanism of Nrf2/ARE …

X Meng, G Sun, J Ye, H Xu, H Wang, X Sun - Free radical research, 2014 - Taylor & Francis
Abstract Notoginsenoside R1 (NGR1), a novel phytoestrogen isolated from Panax
notoginseng, has antioxidant and anti-apoptotic properties. Oxidative stress plays a pivotal …

Girl power in glaucoma: the role of estrogen in primary open angle glaucoma

K Fotesko, BSV Thomsen, M Kolko, R Vohra - Cellular and Molecular …, 2022 - Springer
Estrogen is essential in maintaining various physiological features in women, and a decline
in estrogen levels are known to give rise to numerous unfortunate symptoms associated with …

Kaempferol promotes primordial follicle activation through the phosphatidylinositol 3‐kinase/protein kinase B signaling pathway and reduces DNA fragmentation of …

JMS Santos, T Lins, RS Barberino… - Molecular …, 2019 - Wiley Online Library
The aim of this study was to evaluate the effects of kaempferol on the morphology, follicular
activation, growth, and DNA fragmentation of ovine preantral follicles cultured in situ, and the …

Supplementation of kaempferol to in vitro maturation medium regulates oxidative stress and enhances subsequent embryonic development in vitro

Y Zhao, Y Xu, Y Li, Q Jin, J Sun, E Zhiqiang, Q Gao - Zygote, 2020 - cambridge.org
Kaempferol (KAE) is one of the most common dietary flavonols possessing biological
activities such as anticancer, anti-inflammatory and antioxidant effects. Although previous …

[HTML][HTML] Kaempferol induces ATM/p53-mediated death receptor and mitochondrial apoptosis in human umbilical vein endothelial cells

CF Lee, JS Yang, FJ Tsai… - International …, 2016 - spandidos-publications.com
Kaempferol is a member of the flavonoid compounds found in vegetables and fruits. It is
shown to exhibit biological impact and anticancer activity, but no report exists on the …

Iodoacetic Acid Activates Nrf2-Mediated Antioxidant Response in Vitro and in Vivo

S Wang, W Zheng, X Liu, P Xue, S Jiang… - … science & technology, 2014 - ACS Publications
Iodoacetic acid (IAA) is an unregulated drinking-water disinfection byproduct with potent
cytotoxicity, genotoxicity, and tumorigenicity in animals. Oxidative stress is thought to be …

Female mice exhibit abdominal aortic aneurysm protection in an established rupture model

AZ Fashandi, M Spinosa, M Salmon, G Su… - Journal of Surgical …, 2020 - Elsevier
Background Male gender is a well-established risk factor for abdominal aortic aneurysm
(AAA), whereas estrogen is hypothesized to play a protective role. Although rupture rates …

Phytoestrogen β-Ecdysterone Protects PC12 Cells Against MPP+-Induced Neurotoxicity In Vitro: Involvement of PI3K-Nrf2-Regulated Pathway

Y Zou, R Wang, H Guo, M Dong - Toxicological sciences, 2015 - academic.oup.com
Epidemiological studies have strongly linked postmenopausal estrogens uptake with a
reduced risk of developing Parkinson's disease (PD) in women. Estrogen replacement …

[HTML][HTML] Investigating endocrine disrupting impacts of nine disinfection byproducts on human and zebrafish estrogen receptor alpha

SA Lee, CG Park, M Esterhuizen, I Choi… - Frontiers in Bioscience …, 2023 - imrpress.com
Background: Disinfection byproducts (DBPs) cause endocrine disruption via estrogenic or
anti-estrogenic effects on estrogen receptors. However, most studies have focused on …