Acute inflammatory lesions of the placenta consist of diffuse infiltration of neutrophils at
different sites in the organ. These lesions include acute chorioamnionitis, funisitis, and …

Inflammation is essential for successful embryo implantation, pregnancy maintenance and
delivery. In the last decade, important advances have been made in regard to endogenous …

Energy metabolism plays a crucial role in the immune system. In addition to providing vital
energy for cell growth, reproduction and other cell activities, the metabolism of nutrients such …

Introduction: Intra-amniotic inflammation is traditionally defined as an elevation of amniotic
fluid interleukin (IL)-6. Previous case control studies have suggested an association …

Preterm infants (ie., born before< 37 wk of gestation) are at increased risk of morbidity and
mortality and long-term disabilities. Global prevalence of preterm birth (PTB) varies from 5 to …

Objective: Recent studies indicate that clinical chorioamnionitis is a heterogeneous
condition and only approximately one-half of the patients have bacteria in the amniotic …

Preterm birth (PTB) is a leading cause of neonatal mortality and morbidity worldwide, and
represents a heavy economic and social burden. Despite its broad etiology, PTB has been …

The change from the state of pregnancy to the state of parturition, which we call uterine
transitioning, requires the actions of inflammatory mediators and results in an activated …

STUDY QUESTION Which inflammation biomarkers detected in the vaginal fluid are most
informative for identifying preterm delivery (PTD) risk? SUMMARY ANSWER Elevated …

Preterm birth continues to be one of the most important issues in current obstetric medicine,
being the single largest cause of perinatal morbidity and mortality. The signals that initiate …