User profiles for YUH-FUNG CHEN
 | Chen Yuh-FungChina Medical University (TAIWAN) Verified email at cmu.edu.tw Cited by 2283 |
Anti-inflammatory and analgesic activities from roots of Angelica pubescens
YF Chen, HY Tsai, TS Wu - Planta medica, 1995 - thieme-connect.com
In the present study, we extracted Angelica pubescens (AP) with various solvents in order to
find the bioactive constituents that demonstrated analgesic and anti-inflammatory effects. …
find the bioactive constituents that demonstrated analgesic and anti-inflammatory effects. …
μ Opioid receptor knockout in mice: effects on ligand-induced analgesia and morphine lethality
The μ opioid receptor gene (MOR) was mutated in mice by a gene targeting procedure. In
these MOR-knockout mice, the analgesic effects of morphine, its major metabolites, morphine-…
these MOR-knockout mice, the analgesic effects of morphine, its major metabolites, morphine-…
Leptin-induced IL-6 production is mediated by leptin receptor, insulin receptor substrate-1, phosphatidylinositol 3-kinase, Akt, NF-κB, and p300 pathway in microglia
…, HY Tsai, MC Kao, WM Fu, YF Chen - The Journal of …, 2007 - journals.aai.org
Leptin, the adipocyte-secreted hormone that centrally regulates weight control, is known to
function as an immunomodulatory regulator. We investigated the signaling pathway involved …
function as an immunomodulatory regulator. We investigated the signaling pathway involved …
Naringin-induced bone morphogenetic protein-2 expression via PI3K, Akt, c-Fos/c-Jun and AP-1 pathway in osteoblasts
JB Wu, YC Fong, HY Tsai, YF Chen, M Tsuzuki… - European journal of …, 2008 - Elsevier
Osteoporosis is a reduction in skeletal mass due to an imbalance between bone resorption
and bone formation. Bone morphogenetic protein (BMP) plays important roles in osteoblastic …
and bone formation. Bone morphogenetic protein (BMP) plays important roles in osteoblastic …
SDF-1alpha up-regulates interleukin-6 through CXCR4, PI3K/Akt, ERK, and NF-kappaB-dependent pathway in microglia
Stromal cell-derived factor-1 (SDF-1), also known as CXCL12, and its receptor CXC chemokine
receptor 4 (CXCR4) express in various kinds of cells in central nervous system. The SDF-…
receptor 4 (CXCR4) express in various kinds of cells in central nervous system. The SDF-…
Cantharidin induces G2/M phase arrest and apoptosis in human colorectal cancer colo 205 cells through inhibition of CDK1 activity and caspase-dependent signaling …
Cantharidin (CTD) is a traditional Chinese medicine and an effective component isolated
from blister beetle, and it has been demonstrated to have anticancer, antibiotic, antivirus …
from blister beetle, and it has been demonstrated to have anticancer, antibiotic, antivirus …
Hispolon from Phellinus linteus has antiproliferative effects via MDM2-recruited ERK1/2 activity in breast and bladder cancer cells
…, JB Wu, CH Wu, TC Yang, A Iizuka, YF Chen - Food and chemical …, 2009 - Elsevier
The MDM2 proto-oncogene is overexpressed in many human tumors. Although MDM2
inhibits tumor-suppressor function of p53, there exists a p53-independent role for MDM2 in …
inhibits tumor-suppressor function of p53, there exists a p53-independent role for MDM2 in …
Trans-cinnamaldehyde, an essential oil in cinnamon powder, ameliorates cerebral ischemia-induced brain injury via inhibition of neuroinflammation through …
YF Chen, YW Wang, WS Huang, MM Lee… - Neuromolecular …, 2016 - Springer
Trans-cinnamaldehyde (TCA), an essential oil in cinnamon powder, may have beneficial
effects as a treatment for stroke which is the second leading cause of death worldwide. Post-…
effects as a treatment for stroke which is the second leading cause of death worldwide. Post-…
Curcumin-induced cell cycle arrest and apoptosis in human acute promyelocytic leukemia HL-60 cells via MMP changes and caspase-3 activation
…, HL Lin, MF Tsou, YT Lin, HY Tsai, YF Chen… - Anticancer …, 2006 - ar.iiarjournals.org
Curcumin (diferuloylmethane), is a natural product derived from the root of the plant Curcuma
longa. For centuries, it has been used as a spice and as a herbal medicine in Chinese …
longa. For centuries, it has been used as a spice and as a herbal medicine in Chinese …
[HTML][HTML] Green tea extract ameliorates learning and memory deficits in ischemic rats via its active component polyphenol epigallocatechin-3-gallate by modulation of …
Ischemic stroke results in brain damage and behavioral deficits including memory impairment.
Protective effects of green tea extract (GTex) and its major functional polyphenol (−)-…
Protective effects of green tea extract (GTex) and its major functional polyphenol (−)-…