Resveratrol inhibits human breast cancer cell growth and may mitigate the effect of linoleic acid, a potent breast cancer cell stimulator

H Nakagawa, Y Kiyozuka, Y Uemura, H Senzaki… - Journal of cancer …, 2001 - Springer
Resveratrol is a naturally occurring product found in grapes and wine. The effect of synthetic
resveratrol on the growth of estrogen receptor (ER)-positive (KPL-1 and MCF-7) and -…

Perillyl Alcohol Inhibits Human Breast Cancer Cell Growth in vitro and in vivo

…, N Danbara, M Tsujita-Kyutoku, Y Kiyozuka… - Breast cancer research …, 2004 - Springer
The effect of monoterpene perillyl alcohol (POH) on cell growth, cell cycle progression, and
expression of cell cycle-regulatory proteins in estrogen receptor (ER)-positive (KPL-1 and …

Dietary factors modifying breast cancer risk and relation to time of intake

A Tsubura, N Uehara, Y Kiyozuka, N Shikata - Journal of mammary gland …, 2005 - Springer
Multiple factors contribute to the development of human breast cancer. However, environmental
factors, especially dietary factors, appear to have the greatest effects. Evidence obtained …

Caspase-3 inhibitor rescues N-methyl-N-nitrosourea-induced retinal degeneration in Sprague–Dawley rats

…, J Yang, H Senzaki, Y Uemura, Y Kiyozuka… - Experimental eye …, 2000 - Elsevier
The effect of a caspase-3 inhibitor on N -methyl- N -nitrosourea (MNU)-induced retinal
degeneration was investigated. Sixty mgkg −1 MNU was given intraperitoneally to 50 day old …

Effects of genistein and synergistic action in combination with eicosapentaenoic acid on the growth of breast cancer cell lines

H Nakagawa, D Yamamoto, Y Kiyozuka… - Journal of cancer …, 2000 - Springer
Genistein, a prominent isoflavone in soy products, produced dose- and time-dependent in
vitro growth inhibition at high concentrations (at least 185 μM) with an IC 50 of 7.0–274.2 μM …

An autopsy case of hepatoid carcinoma of the ovary with PIVKA‐II production: Immunohistochemical study and literature review

H Senzaki, Y Kiyozuka, H Mizuoka… - Pathology …, 1999 - Wiley Online Library
A case of hepatoid carcinoma of the ovary in a 61‐year‐old Japanese woman, who showed
high serum levels of α‐fetoprotein and CA125, is reported. Grossly, the left ovarian tumor, …

Adenoid basal carcinoma of the uterine cervix: immunohistochemical study and literature review

…, T Osaki, Y Uemura, Y Kiyozuka… - Japanese journal of …, 1997 - academic.oup.com
Adenoid basal carcinoma of the uterine cervix is rare and its cell origin is still obscure. We
report a case of adenoid basal carcinoma of the uterine cervix discovered incidentally in a 69-…

Cycloprodigiosin hydrochloride, a H+/Cl symporter, induces apoptosis in human breast cancer cell lines

D Yamamoto, Y Kiyozuka, Y Uemura… - Journal of cancer …, 2000 - Springer
The effect of cycloprodigiosin hydrochloride (cPrG · HCl), a H + /Cl − symporter, on five
human breast cancer cell lines (KPL-1, T-47D, MCF-7, MKL-F, and MDA-MB-231), a human …

Effects of fatty acids on liver metastasis of ACL‐15 rat colon cancer cells

S Iwamoto, H Senzaki, Y Kiyozuka, E Ogura, H Takada… - 1998 - Taylor & Francis
The effects of eicosapentaenoic acid [EPA; n‐3 polyunsaturated fatty acid (PUFA)], linoleic
acid (LA; n‐6 PUFA), and palmitic acid (PA; saturated fatty acid) on 1,2‐dimethylhydrazine‐…

Caspase-3 inhibitor transiently delays inherited retinal degeneration in C3H mice carrying the rd gene

…, H Nambu, J Yang, H Senzaki, Y Kiyozuka… - Graefe's archive for …, 2002 - Springer
Background: The effect of a caspase-3 inhibitor on retinal degeneration in C3H mice carrying
the rd gene, a mutation of a rod-specific phosphodiesterase, was investigated. Methods: A …