BACKGROUND: IL-31 is a novel T-cell–derived cytokine that induces severe pruritus and
dermatitis in transgenic mice, and signals through a heterodimeric receptor composed of IL-31 …

Background Hereditary angioedema is characterized by recurrent attacks of angioedema of
the skin, larynx, and gastrointestinal tract. Bradykinin is the key mediator of symptoms. …

Purpose: The microenvironment of head and neck squamous cell carcinomas (HNSCC) is
highly immunosuppressive. HNSCCs expressing elevated levels of PD-L1 have especially …

Molecular prognostic indicators for oropharyngeal squamous cell carcinoma (OSCC), including
HPV‐DNA detection, epidermal growth factor receptor (EGFR) and p16 expression, have …

Spontaneous apoptosis was observed in a proportion of peripheralblood mononuclear cells
obtained from patients withhead and neck cancer (HNC) but not from normal healthy donors …

Initiation, growth, recurrence, and metastasis of head and neck squamous cell carcinomas (HNSCC)
have been related to the behavior of cancer stem cells (CSC) that can be identified …

The progression of epithelial cancer is associated with an intense immunological interaction
between the tumor cells and immune cells of the host. However, little is known about the …

Background Angioedema induced by treatment with angiotensin-converting–enzyme (ACE)
inhibitors accounts for one third of angioedema cases in the emergency room; it is usually …

In patients with cervical cancer of an unknown primary (CUP), no established concept exists
for the necessary diagnostic procedures. In order to find the primary tumor, extensive …

STUDY OBJECTIVE: The pathophysiology of angiotensin-converting enzyme inhibitor (ACEi)–induced
angioedema most likely resembles that of hereditary angioedema, ie, it is mainly …