Background: Datopotamab deruxtecan (Dato-DXd) is an antibody-drug conjugate
consisting of a humanized anti-TROP2 IgG1 monoclonal antibody conjugated to a potent …

Inflammatory breast cancer (IBC) is a rare and aggressive disease. Previous studies have
shown that among patients with stage III breast cancer, IBC is associated with a worse …

Importance Different adjuvant chemotherapy regimens are available for early-stage breast
cancer. Because conventional meta-analysis does not allow comparing all regimens, we …

c-Jun N-terminal kinase (JNK) plays a vital role in malignant transformation of different cancers,
and JNK is highly activated in basal-like triple-negative breast cancer (TNBC). However, …

Background K-912 also known as NC-6300 is a novel epirubicin pro-drug conjugate developed
using micellar nanoparticle technology. We conducted a first-in-human, Phase 1, open-…

Inflammatory breast cancer (IBC) is the most aggressive form of breast cancer. Despite
extensive study, whether inflammation contributes to the tumorigenicity or aggressiveness of IBC …

The formation of premetastatic niches creates a fertile environment for the seeding of
disseminated cancer cells in selected secondary organs. This is crucial for the development of …

Introduction Because of its high rate of metastasis, inflammatory breast cancer (IBC) has a
poor prognosis compared with non-inflammatory types of breast cancer (non-IBC). In a recent …

Inflammatory breast cancer (IBC) is the most lethal and aggressive type of breast cancer,
with a strong proclivity to metastasize, and IBC-specific targeted therapies have not yet been …

In Japan, the social (medical) health‐care system is on the way to being developed to advance
personalized medicine through the implementation of cancer genomic medicine, known …