[PDF][PDF] Epidermal growth factor receptor inhibition attenuates liver fibrosis and development of hepatocellular carcinoma

BC Fuchs, Y Hoshida, T Fujii, L Wei, S Yamada… - …, 2014 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the most rapidly increasing cause of cancer‐related
mortality in the United States. Because of the lack of viable treatment options for HCC, …

Meflin-positive cancer-associated fibroblasts inhibit pancreatic carcinogenesis

…, M Matsuyama, T Kobayashi, T Fujii, S Yamada… - Cancer research, 2019 - AACR
Suguru Yamada; Suguru Yamada … Conklin, Hisashi Haga, Arata Nagasaka, Takaki Miyata,
Makoto Matsuyama, Tomoe Kobayashi, Tsutomu Fujii, Suguru Yamada, Junpei Yamaguchi, …

[HTML][HTML] Mouse model of carbon tetrachloride induced liver fibrosis: Histopathological changes and expression of CD133 and epidermal growth factor

T Fujii, BC Fuchs, S Yamada, GY Lauwers, Y Kulu… - BMC …, 2010 - Springer
Background In the setting of chronic liver injury in humans, epidermal growth factor (EGF) and
EGF receptor (EGFR) are up-regulated and have been proposed to have vital roles in both …

Correlation between radiographic classification and pathological grade of portal vein wall invasion in pancreatic head cancer

…, A Kanzaki, T Fujii, Y Kodera, S Yamada… - Annals of …, 2012 - journals.lww.com
Objectives A retrospective study was performed to clarify the correlation between radiographic
type of portal vein (PV) invasion and pathological grade of PV wall invasion, and their …

[PDF][PDF] Molecular liver cancer prevention in cirrhosis by organ transcriptome analysis and lysophosphatidic acid pathway inhibition

…, T Higashi, S Ghoshal, RS Kim, CB Bian, S Yamada… - Cancer cell, 2016 - cell.com
Cirrhosis is a milieu that develops hepatocellular carcinoma (HCC), the second most lethal
cancer worldwide. HCC prediction and prevention in cirrhosis are key unmet medical needs. …

Modified Blumgart anastomosis for pancreaticojejunostomy: technical improvement in matched historical control study

T Fujii, H Sugimoto, S Yamada, M Kanda… - Journal of …, 2014 - Elsevier
Background Postoperative pancreatic fistula (POPF) is the main cause of fatal complications
after pancreatoduodenectomy. There is still no universally accepted technique for …

A functional polymorphism in the epidermal growth factor gene is associated with risk for hepatocellular carcinoma

BKA Dayyeh, M Yang, BC Fuchs, DL Karl, S Yamada… - Gastroenterology, 2011 - Elsevier
BACKGROUND & AIMS: A single nucleotide polymorphism 61*G (rs4444903) in the
epidermal growth factor (EGF) gene has been associated, in 2 case-control studies, with …

Results of a phase II study on the use of neoadjuvant chemotherapy (FOLFIRINOX or GEM/nab-PTX) for borderline-resectable pancreatic cancer (NUPAT-01)

J Yamaguchi, Y Yokoyama, T Fujii, S Yamada… - 2022 - journals.lww.com
Objective: Given the frequent adverse events with multidrug chemotherapy, not only the
survival benefit but also the feasibility of using neoadjuvant chemotherapy to treat pancreatic …

[HTML][HTML] Nutritional predictors for postoperative short-term and long-term outcomes of patients with gastric cancer

…, M Fujiwara, N Iwata, M Hayashi, S Yamada… - Medicine, 2016 - journals.lww.com
Evidence indicates that impaired immunocompetence and nutritional status adversely affect
short-term and long-term outcomes of patients with cancer. We aimed to evaluate the clinical …

Epithelial-to-mesenchymal transition predicts prognosis of pancreatic cancer

S Yamada, BC Fuchs, T Fujii, Y Shimoyama… - Surgery, 2013 - Elsevier
Background Pancreatic cancer has a dismal prognosis that is attributed to common local
invasiveness and metastasis. Epithelial-to-mesenchymal transition (EMT) plays an important …