von Hippel-Lindau disease is a heritable multisystem cancer syndrome that is associated with
a germline mutation of the VHL tumour suppressor gene on the short arm of chromosome …

Purpose: A novel nanomedicine, CYT-6091, constructed by simultaneously binding recombinant
human tumor necrosis factor alpha (rhTNF) and thiolyated polyethylene glycol to the …

Adrenal aldosterone-producing adenomas (APAs) constitutively produce the salt-retaining
hormone aldosterone and are a common cause of severe hypertension. Recurrent mutations …

Purpose: To determine if pulsed-high intensity focused ultrasound (HIFU) could effectively
serve as a source of hyperthermia with thermosensitive liposomes to enhance delivery and …

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant cancer syndrome,
characterized primarily by multiple tumors in the parathyroid glands, endocrine pancreas, and …

We have demonstrated previously the oncolytic effects of a systemically delivered, replicating
vaccinia virus. To enhance the tumor specificity of this vector, we have developed a …

Purpose: Malignant mesothelioma (MM) arising in the peritoneal cavity is a rare neoplasm
characterized by peritoneal progression and for which there are limited therapeutic options. …

While altered expression of microRNAs (miRs) in tumors has been well documented, it
remains unclear how the miR transcriptome intersects neoplastic progression. By profiling the …

BACKGROUND: von Hippel-Lindau (vHL) disease is an autosomal dominant syndrome
associated with neoplasms in multiple organs, which includes the pancreas. Here, we report the …

This manuscript is the result of the North American Neuroendocrine Tumor Society consensus
conference on the surgical management of pancreatic neuroendocrine tumors from July …