Unique autoantibody prevalence in long-term recovered SARS-CoV-2-infected individuals

H Lingel, S Meltendorf, U Billing, C Thurm, K Vogel… - Journal of …, 2021 - Elsevier
The variability in resolution of SARS-CoV-2-infections between individuals neither is
comprehended, nor are the long-term immunological consequences. To assess the long-term …

[HTML][HTML] Thyroid cancer cells in space during the TEXUS-53 sounding rocket mission–The THYROID Project

…, M Wehland, MZ Nassef, D Melnik, S Meltendorf… - Scientific Reports, 2018 - nature.com
Human follicular thyroid cancer cells (FTC-133) were sent to space via a sounding rocket
during the TEXUS-53 mission to determine the impact of short-term microgravity on these cells. …

Age-related differences in immune reactions to SARS-CoV-2 spike and nucleocapsid antigens

P Morhart, S Kehl, W Schuh, K Hermes, S Meltendorf… - in vivo, 2023 - iv.iiarjournals.org
Background/Aim: The manifestation and severity of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infections show a clear correlation to the age of a patient. The …

[HTML][HTML] RSK-mediated nuclear accumulation of the cold-shock Y-box protein-1 controls proliferation of T cells and T-ALL blasts

S Gieseler-Halbach, S Meltendorf, M Pierau… - Cell Death & …, 2017 - nature.com
Deregulated proliferation is key to tumor progression. Although unrestricted proliferation of
solid tumor cells correlates with the cold-shock protein Y-box (YB)-binding protein-1 …

IL‐13 determines specific IgE responses and SARS‐CoV‐2 immunity after mild COVID‐19 and novel mRNA vaccination

S Meltendorf, K Vogel, C Thurm… - European Journal of …, 2022 - Wiley Online Library
After recovery, mild and severe COVID‐19 diseases are associated with long‐term effects
on the host immune system, such as prolonged T‐cell activation or accumulation of …

[PDF][PDF] Cell survival failure in effector T cells from patients with systemic lupus erythematosus following insufficient up‐regulation of cold‐shock Y‐box binding protein 1

S Meltendorf, H Fu, M Pierau… - Arthritis & …, 2020 - Wiley Online Library
Objective The importance of cold‐shock Y‐box binding protein 1 (YB‐1) for cell homeostasis
is well‐documented based on prior observations of its association with certain cancer …

Effective assessment of CD4+ T cell Immunodominance patterns: impact of antigen processing and HLA restriction

M Alvaro-Benito, ET Abualrous, H Lingel, S Meltendorf… - bioRxiv, 2024 - biorxiv.org
Identifying T cell epitopes is essential for studying and potentially tuning immune responses
to pathogens. The polymorphic nature of major histocompatibility complex of class II (MHCII)-…

Comparing alternative ranibizumab dosages for safety and efficacy in retinopathy of prematurity: a randomized clinical trial

…, I Oberacher-Velten, R Guthoff, S Meltendorf… - JAMA …, 2018 - jamanetwork.com
Importance Anti–vascular endothelial growth factor (VEGF) therapies are a novel treatment
option in retinopathy of prematurity (ROP). Data on dosing, efficacy, and safety are insufficient…

transferGWAS: GWAS of images using deep transfer learning

M Kirchler, S Konigorski, M Norden, C Meltendorf… - …, 2022 - academic.oup.com
Motivation Medical images can provide rich information about diseases and their biology.
However, investigating their association with genetic variation requires non-standard methods. …

Ranibizumab in retinopathy of prematurity–one‐year follow‐up of ophthalmic outcomes and two‐year follow‐up of neurodevelopmental outcomes from the CARE …

…, S Schwarz, A Ehmer, S Meltendorf… - Acta …, 2022 - Wiley Online Library
Purpose The primary endpoint results from the comparing alternative ranibizumab dosages
for safety and efficacy in retinopathy of prematurity (CARE‐ROP) core study identified …