User profiles for SILVIA MEZI

Silvia Mezi

sapienza universita' di roma
Verified email at uniroma1.it
Cited by 2131

FOLFOXIRI plus bevacizumab versus FOLFIRI plus bevacizumab as first-line treatment of patients with metastatic colorectal cancer: updated overall survival and …

…, C Antoniotti, C Lupi, E Sensi, S Lonardi, S Mezi… - The Lancet …, 2015 - thelancet.com
Background In the TRIBE study, FOLFOXIRI (fluorouracil, leucovorin, oxaliplatin, and
irinotecan) plus bevacizumab significantly improved progression-free survival of patients with …

[HTML][HTML] Anti–PD-1 and anti–PD-L1 in head and neck cancer: a network meta-analysis

…, A Polimeni, M Nuti, MC Merlano, S Mezi… - Frontiers in …, 2021 - frontiersin.org
Objective The monoclonal antibodies anti-programmed death protein-1 (anti–PD-1)
nivolumab and pembrolizumab are the first immune checkpoint inhibitors (ICIs) approved for …

[HTML][HTML] The agnostic role of site of metastasis in predicting outcomes in cancer patients treated with immunotherapy

…, M Ghidini, G D'Amati, C Della Rocca, S Mezi… - Vaccines, 2020 - mdpi.com
Immune checkpoint inhibitors have revolutionized treatment and outcome of melanoma and
many other solid malignancies including non-small cell lung cancer (NSCLC) and renal cell …

Incidence and risk of pulmonary toxicity in patients treated with mTOR inhibitors for malignancy. A meta-analysis of published trials

R Iacovelli, A Palazzo, S Mezi, F Morano, G Naso… - Acta …, 2012 - Taylor & Francis
Background. mTOR inhibitors are currently used in the treatment of solid malignancies. Since
their approval, several cases of pulmonary toxicity (PT) have been described. This analysis …

[HTML][HTML] Tobacco, alcohol and family history of cancer as risk factors of Oral Squamous Cell Carcinoma: Case-control retrospective study

…, D Musio, CRT Di Gioia, D Messineo, S Mezi… - Applied Sciences, 2020 - mdpi.com
The aim of the study is to observe retrospectively the correlation between Oral Squamous
Cell Carcinoma (OSCC) and risk factors; including tobacco, alcohol and Family History of …

Incidence and relative risk of hepatic toxicity in patients treated with anti‐angiogenic tyrosine kinase inhibitors for malignancy

…, P Trenta, A De Benedetto, S Mezi… - British journal of …, 2014 - Wiley Online Library
Aim The aim of this study is to investigate the incidence and risk of hepatic toxicity in patients
receiving tyrosine kinase inhibitors ( TKIs ) through a large up‐to‐date meta‐analysis of …

Follow-up program in head and neck cancer

…, M de Vincentiis, V Valentini, D Musio, S Mezi… - Critical Reviews in …, 2017 - Elsevier
… Author links open overlay panel Francesca De Felice a , Marco de Vincentiis b , Valentino
Valentini c , Daniela Musio a , Silvia Mezi d , Luigi Lo Mele e , Valentina Terenzi c , Vittorio D’…

[HTML][HTML] The role of soluble LAG3 and soluble immune checkpoints profile in advanced head and neck cancer: a pilot study

…, F Scirocchi, A Rughetti, M Nuti, S Mezi… - Journal of Personalized …, 2021 - mdpi.com
Unresectable recurrent and/or metastatic head and neck squamous cell carcinoma (R/M
HNSCC) has a very poor prognosis. Soluble immune checkpoints (sICs) are circulating proteins …

[HTML][HTML] The role of immune profile in predicting outcomes in cancer patients treated with immunotherapy

…, IG Zizzari, E Cortesi, S Tomao, M Nuti, S Mezi… - Frontiers in …, 2022 - frontiersin.org
Background Despite the efficacy of immunotherapy, only a small percentage of patients
achieves a long-term benefit in terms of overall survival. The aim of this study was to define an …

[HTML][HTML] Tryptophan catabolism as immune mechanism of primary resistance to anti-PD-1

A Botticelli, S Mezi, G Pomati, B Cerbelli… - Frontiers in …, 2020 - frontiersin.org
Background: Clinical trials showed that only a subset of patients benefits from immunotherapy,
suggesting the need to identify new predictive biomarker of resistance. Indoleamine-2,3-…