[HTML][HTML] Targeting AKT with costunolide suppresses the growth of colorectal cancer cells and induces apoptosis in vitro and in vivo
H Huang, S Park, H Zhang, S Park, W Kwon… - Journal of Experimental …, 2021 - Springer
Background Colorectal cancer (CRC) is a clinically challenging malignant tumor worldwide.
As a natural product and sesquiterpene lactone, Costunolide (CTD) has been reported to …
As a natural product and sesquiterpene lactone, Costunolide (CTD) has been reported to …
[6]-gingerol suppresses oral cancer cell growth by inducing the activation of AMPK and suppressing the AKT/mTOR signaling pathway
H Zhang, E Kim, J Yi, H Hai, H Kim, S Park, SG Lim… - in vivo, 2021 - iv.iiarjournals.org
Background/Aim: [6]-Gingerol, a compound extracted from ginger, has been studied for its
therapeutic potential in various types of cancers. However, its effects on oral cancer remain …
therapeutic potential in various types of cancers. However, its effects on oral cancer remain …
[HTML][HTML] Protective effect of GIP against monosodium glutamate-induced ferroptosis in mouse hippocampal HT-22 cells through the MAPK signaling pathway
The effect of glucose-dependent insulinotropic polypeptide (GIP) on cells under oxidative
stress induced by glutamate, a neurotransmitter, and the underlying molecular mechanisms …
stress induced by glutamate, a neurotransmitter, and the underlying molecular mechanisms …
Effects of Al and Ta on the high temperature oxidation of Ni-based superalloys
SJ Park, SM Seo, YS Yoo, HW Jeong, HJ Jang - Corrosion science, 2015 - Elsevier
The effects of Al and Ta on the high temperature oxidation of Ni–8Cr–9.5Co–2.5Mo–6W–(4–5)Al–2Ti–(3–6)Ta–0.1C–0.01B
(wt.%) superalloys were examined at 850 C and 1000 C by …
(wt.%) superalloys were examined at 850 C and 1000 C by …
[HTML][HTML] Rhein Induces Oral Cancer Cell Apoptosis and ROS via Suppresse AKT/mTOR Signaling Pathway In Vitro and In Vivo
…, E Kim, J Yi, H Huang, H Kim, MA Raza, S Park… - International Journal of …, 2023 - mdpi.com
Oral cancer remains the leading cause of death worldwide. Rhein is a natural compound
extracted from the traditional Chinese herbal medicine rhubarb, which has demonstrated …
extracted from the traditional Chinese herbal medicine rhubarb, which has demonstrated …
[6]-Shogaol inhibits growth and induces apoptosis of non-small cell lung cancer cells by directly regulating Akt1/2
Non-small cell lung cancer (NSCLC) is the leading cause of cancer mortality worldwide.
Despite progress in developing chemotherapeutics for the treatment of NSCLC, primary and …
Despite progress in developing chemotherapeutics for the treatment of NSCLC, primary and …
[HTML][HTML] Rhein suppresses colorectal cancer cell growth by inhibiting the mTOR pathway in vitro and in vivo
H Zhang, JK Yi, H Huang, S Park, S Park, W Kwon… - Cancers, 2021 - mdpi.com
Simple Summary Colorectal cancer (CRC) is the fourth most common cancer and the second
most common cause of cancer-related deaths globally. Rhein is a natural anthraquinone …
most common cause of cancer-related deaths globally. Rhein is a natural anthraquinone …
[HTML][HTML] Costunolide induces apoptosis via the reactive oxygen species and protein kinase B pathway in Oral cancer cells
H Huang, JK Yi, SG Lim, S Park, H Zhang… - International Journal of …, 2021 - mdpi.com
Oral cancer (OC) has been attracted research attention in recent years as result of its high
morbidity and mortality. Costunolide (CTD) possesses potential anticancer and bioactive …
morbidity and mortality. Costunolide (CTD) possesses potential anticancer and bioactive …
[HTML][HTML] 20 (S)-ginsenoside Rh2 inhibits colorectal cancer cell growth by suppressing the Axl signaling pathway in vitro and in vivo
H Zhang, JK Yi, H Huang, S Park, W Kwon… - Journal of ginseng …, 2022 - Elsevier
Background Colorectal cancer (CRC) has a high morbidity and mortality worldwide. 20 (S)-ginsenoside
Rh2 (G-Rh2) is a natural compound extracted from ginseng, which exhibits …
Rh2 (G-Rh2) is a natural compound extracted from ginseng, which exhibits …
[HTML][HTML] Overexpression of cathepsin S induces chronic atopic dermatitis in mice
Atopic dermatitis (AD) is a chronically relapsing, noncontagious pruritic skin disease with
two phases: acute and chronic. Previous studies have shown that the cysteine protease …
two phases: acute and chronic. Previous studies have shown that the cysteine protease …