Preparation and characterization of nanoparticles shelled with chitosan for oral insulin delivery

YH Lin, FL Mi, CT Chen, WC Chang, SF Peng… - …, 2007 - ACS Publications
Nanoparticles (NPs) composed of chitosan (CS) and poly(γ-glutamic acid) (γ-PGA) were
prepared by a simple ionic-gelation method for oral insulin delivery. Fourier transform infrared (…

The characteristics, cellular uptake and intracellular trafficking of nanoparticles made of hydrophobically-modified chitosan

YL Chiu, YC Ho, YM Chen, SF Peng, CJ Ke… - Journal of Controlled …, 2010 - Elsevier
It has been reported that nanoparticles (NPs) prepared by hydrophobically-modified polymers
could accumulate passively in the tumor tissue; however, their cellular uptake mechanism …

Mechanisms of cellular uptake and intracellular trafficking with chitosan/DNA/poly (γ-glutamic acid) complexes as a gene delivery vector

SF Peng, MT Tseng, YC Ho, MC Wei, ZX Liao… - Biomaterials, 2011 - Elsevier
Chitosan (CS)-based complexes have been considered as a vector for DNA delivery;
nonetheless, their transfection efficiency is relatively low. An approach by incorporating poly(γ-…

Development of novel nanoparticles shelled with heparin for berberine delivery to treat Helicobacter pylori

…, CH Lai, YM Hsu, YH Yao, TY Chen, JY Wu, SF Peng… - Acta biomaterialia, 2011 - Elsevier
Various approaches have been proposed to overcome the unpleasant side-effects
associated with antibiotic treatment for Helicobacter pylori. The limited effectiveness of such …

[HTML][HTML] Curcumin-loaded nanoparticles induce apoptotic cell death through regulation of the function of MDR1 and reactive oxygen species in cisplatin-resistant CAR …

PY Chang, SF Peng, CY Lee… - International …, 2013 - spandidos-publications.com
Curcumin is a polyphenolic compound which possesses anticancer potential. It has been
shown to induce cell death in a variety of cancer cells, however, its effect on CAL27‑cisplatin-…

[HTML][HTML] Kaempferol induces autophagy through AMPK and AKT signaling molecules and causes G2/M arrest via downregulation of CDK1/cyclin B in SK-HEP-1 …

WW Huang, SC Tsai, SF Peng… - International …, 2013 - spandidos-publications.com
Kaempferol belongs to the flavonoid family and has been used in traditional folk medicine.
Here, we investigated the antitumor effects of kaempferol on cell cycle arrest and autophagic …

[HTML][HTML] Association between the oxidative balance score and telomere length from the national health and nutrition examination survey 1999-2002

W Zhang, SF Peng, L Chen, HM Chen… - … medicine and cellular …, 2022 - hindawi.com
Purpose. Leukocyte telomere length (LTL) is an important biomarker of aging. The oxidative
balance score (OBS) is used to assess the oxidative stress-related exposures of diet and …

Effects of incorporation of poly (γ-glutamic acid) in chitosan/DNA complex nanoparticles on cellular uptake and transfection efficiency

SF Peng, MJ Yang, CJ Su, HL Chen, PW Lee, MC Wei… - Biomaterials, 2009 - Elsevier
Chitosan (CS)/DNA complex nanoparticles (NPs) have been considered as a vector for gene
delivery. Although advantageous for DNA packing and protection, CS-based complexes …

[HTML][HTML] Kaempferol suppresses cell metastasis via inhibition of the ERK-p38-JNK and AP-1 signaling pathways in U-2 OS human osteosarcoma cells

…, CM Lin, CY Lee, NC Shih, SF Peng… - Oncology …, 2013 - spandidos-publications.com
Kaempferol is a natural flavonoid that possesses anti-proliferative and apoptosis-inducing
activities in several cancer cell lines. In the present study, we investigated the anti-metastatic …

Casticin inhibits human prostate cancer DU 145 cell migration and invasion via Ras/Akt/NF‐κB signaling pathways

…, CH Tang, JS Yang, YM Hsu, SF Peng… - Journal of food …, 2019 - Wiley Online Library
Casticin, a polymethoxyflavone derived from natural plants, has biological activities including
induction of cell apoptosis. In this study, we showed the beneficial effects of casticin on the …