We previously reported that hepatic stellate cells (HSCs) activated by angiotensin II (AngII)
facilitate stromal fibrosis and tumor progression in intrahepatic cholangiocarcinoma (ICC). …

Background/Aim: Severe sepsis is associated with high morbidity and mortality rates.
Inflammation and coagulation play pivotal roles in the pathogenesis of sepsis leading to multiple …

A number of studies have reported that acute lung injury (ALI) and acute respiratory distress
syndrome (ARDS) are independent risk factors for organ dysfunction and mortality in …

Intraperitoneal (ip) chemotherapy with paclitaxel (PTX) has been shown to be a promising
treatment strategy for peritoneal metastasis. The present study focused on the comparative …

Results of surgery alone for pancreatic cancer are disappointing. We retrospectively evaluated
the efficacy and tolerability of neoadjuvant chemotherapy (NAC) with gemcitabine and …

Oxaliplatin‑based chemotherapy plays a central role in the treatment of patients with
colorectal liver metastasis (CRLM). This treatment, however, has been associated with hepatic …

Sinusoidal obstruction syndrome (SOS), previously known as veno‑occlusive disease, is
relatively rare subsequent to liver transplantation (LT). SOS refractory to medical therapy, …

Background: Hepatic sinusoidal obstruction syndrome (SOS), also known as veno-occlusive
disease, is a form of drug-induced liver injury, the initial morphological changes associated …

Esophageal carcinoma is one of the most aggressive malignancies, and is characterized by
poor response to current therapy and a dismal survival rate. In this study we investigated …

Cancer stem cells (CSCs) have self-renewal and pluripotency capabilities and contribute to
cancer progression and chemoresistance. It has been proposed that the treatment …