User profiles for SALEH M. IBRAHIM

Saleh Ibrahim

Professor, Khalifa University, UAE
Verified email at ku.ac.ae
Cited by 9218

Therapeutic efficacy of IL-17 neutralization in murine experimental autoimmune encephalomyelitis

HH Hofstetter, SM Ibrahim, D Koczan, N Kruse… - Cellular …, 2005 - Elsevier
Experimental autoimmune encephalomyelitis (EAE) is widely regarded as an animal model
of the human disease multiple sclerosis. A multitude of studies has investigated the …

[HTML][HTML] Molecular responses to hypoxia in tumor cells

M Kunz, SM Ibrahim - Molecular cancer, 2003 - Springer
Highly aggressive, rapidly growing tumors are exposed to hypoxia or even anoxia which
occurs as a consequence of inadequate blood supply. Both hypoxia and consecutive hypoxia/…

Gene expression signatures for tumor progression, tumor subtype, and tumor thickness in laser-microdissected melanoma tissues

…, SM Ibrahim, G Gross, R Spang, M Kunz - Clinical cancer …, 2007 - AACR
Purpose: To better understand the molecular mechanisms of malignant melanoma
progression and metastasis, gene expression profiling was done of primary melanomas and …

[PDF][PDF] Cytokines and cytokine profiles in human autoimmune diseases and animal models of autoimmunity

M Kunz, SM Ibrahim - Mediators of inflammation, 2009 - downloads.hindawi.com
Autoimmune diseases are a major cause of morbidity and mortality in the industrialized world,
affecting 3–8% of the population. In principle, autoimmunity develops after breaking self-…

[PDF][PDF] Gene expression profiling of peripheral blood mononuclear leukocytes from psoriasis patients identifies new immune regulatory molecules

…, R Guthke, HJ Thiesen, SM Ibrahim… - European Journal of …, 2005 - researchgate.net
In the present report gene expression profiling of peripheral blood mononuclear cells (PBMC)
from psoriasis patients suffering from severe generalized disease was performed …

[HTML][HTML] Analysis of intestinal microbiota in hybrid house mice reveals evolutionary divergence in a vertebrate hologenome

…, R Häsler, A Franke, HH Oberg, SM Ibrahim… - Nature …, 2015 - nature.com
Recent evidence suggests that natural selection operating on hosts to maintain their
microbiome contributes to the emergence of new species, that is, the ‘hologenomic basis of …

Dissecting the effects of mtDNA variations on complex traits using mouse conplastic strains

…, E Kanitz, W Otten, M Kunz, SM Ibrahim - Genome …, 2009 - genome.cshlp.org
Previous reports have demonstrated that the mtDNA of mouse common inbred strains (CIS)
originated from a single female ancestor and that mtDNA mutations occurred during CIS …

[HTML][HTML] Epidermolysis bullosa acquisita: from pathophysiology to novel therapeutic options

…, CD Sadik, K Bieber, SM Ibrahim… - Journal of Investigative …, 2016 - Elsevier
Epidermolysis bullosa acquisita (EBA) is a prototypic organ-specific autoimmune disease
induced by autoantibodies to type VII collagen causing mucocutaneous blisters. In the …

Fas ligation on macrophages enhances IL-1R1–Toll-like receptor 4 signaling and promotes chronic inflammation

Y Ma, H Liu, H Tu-Rapp, HJ Thiesen, SM Ibrahim… - Nature …, 2004 - nature.com
The nonapoptotic functions of Fas ligation are incompletely characterized. In contrast to
expectations, we show here that Fas-deficient mice developed less-severe collagen-induced …

[HTML][HTML] Genome-wide mapping of gene–microbiota interactions in susceptibility to autoimmune skin blistering

…, S Künzel, D Zillikens, JF Baines, SM Ibrahim - Nature …, 2013 - nature.com
Susceptibility to chronic inflammatory diseases is determined by immunogenetic and
environmental risk factors. Resident microbial communities often differ between healthy and …