Amino acids may have protective effects on salivary glands of 5-FU-administered mice

R Fujiwara, K Harada, T Ferdous, K Mishima - in vivo, 2022 - iv.iiarjournals.org
Background/Aim: This study aimed to identify the most useful components of Elental ® in the
treatment of 5-fluorouracil (FU)-induced mucositis and salivary gland atrophy in mice. …

[HTML][HTML] An elemental diet protects mouse salivary glands from 5‑fluorouracil‑induced atrophy

K Harada, T Ferdous, R Fujiwara… - Oncology …, 2022 - spandidos-publications.com
An elemental diet (ED) reduces adverse effects of chemotherapy, including oral mucositis,
in patients with cancer. However, the detailed mechanism (s) of the healing effects of an ED …

[HTML][HTML] Histological verification of the treatment effect of tirabrutinib for relapsed/refractory primary central nervous system lymphoma

Y Okita, R Kano-Fujiwara, SI Nakatsuka… - … Hematology & Oncology, 2021 - Springer
Tirabrutinib (ONO/GS-4059; Ono Pharmaceutical) is a newly developed drug that selectively
and irreversibly inhibits Bruton’s tyrosine kinase (BTK) and has been approved in Japan for …

STK11 loss drives rapid progression in a breast cancer patient resulting in pulmonary tumor thrombotic microangiopathy

F Fujisawa, K Kunimasa, R Kano-Fujiwara, Y Sato… - Breast Cancer, 2021 - Springer
We experienced a case of breast cancer in which liver metastases spread rapidly and the
patient died of pulmonary tumor thrombotic microangiopathy (PTTM). PTTM is a fatal cancer-…

[HTML][HTML] Effects of pre-surgical administration of prostaglandin analogs on the outcome of trabeculectomy

…, M Fujiwara, R Araki, R Kiyoi, Y Shiode, A Fujiwara… - PLoS …, 2017 - journals.plos.org
For primary open angle glaucoma (POAG), laser treatment or surgery is used when the
target intraocular pressure (IOP) cannot be achieved by pharmacological agents, such as …

Skipping breakfast is associated with reproductive dysfunction in post-adolescent female college students

T Fujiwara, R Nakata - Appetite, 2010 - Elsevier
Although increasing attention has been paid to the adverse effects of skipping breakfast on
quality of life, there are very few reports concerning the relationship between skipping …

[HTML][HTML] Analysis of autonomic function during natural defecation in patients with irritable bowel syndrome using real-time recording with a wearable device

…, Y Kojima, T Takeuchi, M Shiba, K Higuchi, Y Fujiwara - Plos one, 2022 - journals.plos.org
Background Autonomic dysfunction is a factor in irritable bowel syndrome (IBS). However,
there are no reports of autonomic nervous system (ANS) activity during natural defecation in …

[HTML][HTML] Neutrophil-to-lymphocyte ratio may predict clinical relapse in ulcerative colitis patients with mucosal healing

…, F Tanaka, Y Nagami, K Taira, N Kamata, Y Fujiwara - PLoS …, 2023 - journals.plos.org
Endoscopic mucosal healing (MH) is an important treatment goal for patients with ulcerative
colitis (UC). The neutrophil-to-lymphocyte ratio (NLR) reflects systemic inflammation and …

[HTML][HTML] Time-restricted feeding regulates circadian rhythm of murine uterine clock

…, T Iizuka, R Nakata, T Fujiwara, H Fujiwara… - Current Developments …, 2021 - Elsevier
Background Skipping breakfast is associated with dysmenorrhea in young women. This
suggests that the delay of food intake in the active phase impairs uterine functions by interfering …

[HTML][HTML] Novel prognostic biomarkers of pouchitis after ileal pouch-anal anastomosis for ulcerative colitis: Neutrophil-to-lymphocyte ratio

…, M Shibutani, H Nagahara, S Ohfuji, Y Fujiwara - PLoS …, 2020 - journals.plos.org
Objectives Pouchitis is a major complication after restorative proctocolectomy with ileal
pouch-anal anastomosis (IPAA) in patients with ulcerative colitis (UC). Although there have been …