User profiles for OSSI NERG

Ossi Nerg

MD, Neurologist, University of Eastern Finland
Verified email at kuh.fi
Cited by 876

[HTML][HTML] Cerebrospinal fluid biomarker and brain biopsy findings in idiopathic normal pressure hydrocephalus

OT Pyykkö, M Lumela, J Rummukainen, O Nerg… - PloS one, 2014 - journals.plos.org
Background The significance of amyloid precursor protein (APP) and neuroinflammation in
idiopathic normal pressure hydrocephalus (iNPH) and Alzheimer's disease (AD) is unknown. …

Incidence, comorbidities, and mortality in idiopathic normal pressure hydrocephalus

OT Pyykkö, O Nerg, HM Niskasaari, T Niskasaari… - World neurosurgery, 2018 - Elsevier
Object To investigate the incidence, comorbidities, mortality, and causes of death in idiopathic
normal pressure hydrocephalus (iNPH). Methods A cohort of 536 patients with possible …

Amyloid-β and tau dynamics in human brain interstitial fluid in patients with suspected normal pressure hydrocephalus

…, AM Koivisto, O Nerg… - Journal of …, 2015 - content.iospress.com
Objective: To assess the relationship between AD-related pathological changes in human
brain tissue, ventricular and lumbar CSF, and brain interstitial fluid (ISF). Methods: Altogether …

Predicting development of Alzheimer's disease in patients with shunted idiopathic normal pressure hydrocephalus

AJ Luikku, A Hall, O Nerg, AM Koivisto… - Journal of …, 2019 - content.iospress.com
Background: Idiopathic normal pressure hydrocephalus (iNPH) patients often develop
Alzheimer’s disease (AD) related brain pathology. Disease State Index (DSI) is a method to …

Searching for explanations for cryptogenic stroke in the young: revealing the triggers, causes, and outcome (SECRETO): rationale and design

…, S Saeed, N Yesilot, P Jäkälä, O Nerg… - European Stroke …, 2017 - journals.sagepub.com
Background Worldwide, about 1.3 million annual ischaemic strokes (IS) occur in adults
aged <50 years. Of these early-onset strokes, up to 50% can be regarded as cryptogenic or …

[HTML][HTML] Prevalence of schizophrenia in idiopathic normal pressure hydrocephalus

…, MI Kurki, M Hiltunen, T Rauramaa, O Nerg… - …, 2019 - journals.lww.com
BACKGROUND Idiopathic normal pressure hydrocephalus (iNPH) is a progressive and
potentially treatable neurodegenerative disease affecting elderly people, characterized by gait …

[HTML][HTML] Effect of different thresholds for CT perfusion volumetric analysis on estimated ischemic core and penumbral volumes

…, J Aherto, H Matikka, H Manninen, O Nerg… - PLoS …, 2021 - journals.plos.org
Purpose This single-center study compared three threshold settings for automated analysis
of the ischemic core (IC) and penumbral volumes using computed tomographic perfusion, …

APOE4 predicts amyloid-β in cortical brain biopsy but not idiopathic normal pressure hydrocephalus

…, JAA Mölsä, J Rummukainen, O Nerg… - Journal of Neurology …, 2012 - jnnp.bmj.com
Objective To investigate the association of apolipoprotein E (APOE) genotype, especially the
APOE4 allele, to (1) idiopathic normal pressure hydrocephalus (iNPH) and (2) amyloid-β (…

The CERAD neuropsychological battery in patients with idiopathic normal pressure hydrocephalus compared with normal population and patients with mild …

O Nerg, A Junkkari, I Hallikainen… - Journal of …, 2021 - content.iospress.com
Background: The usefulness of CERAD Neuropsychological Battery for describing the cognitive
impairment in idiopathic normal pressure hydrocephalus (iNPH) is unknown. Objective: …

Multimodal analysis to predict shunt surgery outcome of 284 patients with suspected idiopathic normal pressure hydrocephalus

AJ Luikku, A Hall, O Nerg, AM Koivisto, M Hiltunen… - Acta …, 2016 - Springer
Objectives Optimal selection of idiopathic normal pressure hydrocephalus (iNPH) patients for
shunt surgery is challenging. Disease State Index (DSI) is a statistical method that merges …