Epithelial-mesenchymal transition (EMT) refers to critical events occasionally observed
during tumor progression, including invasion and metastasis, by which cancer cells acquire a …

We have previously shown that a stromal cell–derived factor-1 (SDF-1; CXCL12)/CXCR4
system is involved in the establishment of lymph node metastasis, but not in that of distant …

Background: The inducible nitric oxide synthase (iNOS) is associated with inflammatory
processes and cancer formation through production of nitric oxide (NO). However, the clinical …

We have previously demonstrated that a stromal cell-derived factor-1 (SDF-1; CXCL12)/CXCR4
system is involved in the establishment of lymph node metastasis in oral squamous cell …

Background We have demonstrated that the stromal cell-derived factor-1 (SDF-1; CXCL12)/CXCR4
system is involved in the establishment of lymph node metastasis in oral squamous …

We evaluated the orally administered S-1, in combination with ionizing radiation both in vivo
and in vitro against human oral cancer cell lines. Human oral cancer cell lines were used as …

It is well known that loss of the cyclin-dependent kinase inhibitor p27 Kip1 protein correlates
with the poor prognosis of various cancers including oral squamous cell carcinoma (SCC). …

S-1 is a new oral antineoplastic agent which can inhibit cell growth and induces apoptosis
in certain types of cancer cells including gastric carcinomas, colorectal cancers and salivary …

In this study, we attempted to use a non-viral gene transfer system, in vivo electroporation,
in oral cancer cell B88 xenografts. To evaluate this in vivo gene transfer method, the GFP …

We have previously demonstrated that distant metastasis might require the autocrine stromal
cell-derived factor-1 (SDF-1; CXCL12)/CXCR4 system in cases of oral squamous cell …