[HTML][HTML] Vascular RAGE transports oxytocin into the brain to elicit its maternal bonding behaviour in mice

…, Y Eguchi, Y Kitao, O Hori, Y Shiraishi, N Ozaki… - Communications …, 2019 - nature.com
Oxytocin sets the stage for childbirth by initiating uterine contractions, lactation and maternal
bonding behaviours. Mice lacking secreted oxcytocin (Oxt −/− , Cd38 −/− ) or its receptor (…

TRP channels and ASICs mediate mechanical hyperalgesia in models of inflammatory muscle pain and delayed onset muscle soreness

Y Fujii, N Ozaki, T Taguchi, K Mizumura, K Furukawa… - Pain, 2008 - Elsevier
The roles of ion channels in sensory neurons were examined in experimental models of
muscle pain in the rat. Rats were injected with 50μl of 4% carrageenan or subjected to an …

Insulin inhibits neuropeptide Y gene expression in the arcuate nucleus through GABAergic systems

I Sato, H Arima, N Ozaki, M Watanabe… - Journal of …, 2005 - Soc Neuroscience
Neuropeptide Y (NPY) in the arcuate nucleus is an orexigenic hormone of which levels are
regulated by humoral as well as neural signals. In this study, we examined the regulation of …

[HTML][HTML] Mechanical allodynia and thermal hyperalgesia induced by experimental squamous cell carcinoma of the lower gingiva in rats

K Nagamine, N Ozaki, M Shinoda, H Asai… - The Journal of …, 2006 - Elsevier
We developed a rat model of oral cancer pain by inoculating cancer cells into the lower
gingiva. A squamous cell carcinoma (SCC) derived from Fisher rats, SCC-158, was inoculated …

Heat and mechanical hyperalgesia in mice model of cancer pain

H Asai, N Ozaki, M Shinoda, K Nagamine, I Tohnai… - Pain, 2005 - journals.lww.com
We developed a mouse model of cancer pain to investigate its underlying mechanisms.
SCC-7, squamous cell carcinoma (SCC) derived from C3H mice, was inoculated …

Repeated intramuscular injections of nerve growth factor induced progressive muscle hyperalgesia, facilitated temporal summation, and expanded pain areas

K Hayashi, S Shiozawa, N Ozaki, K Mizumura… - PAINŽ, 2013 - Elsevier
Intramuscular injection of nerve growth factor (NGF) is known to induce deep-tissue mechanical
hyperalgesia. In this study it was hypothesised that daily intramuscular injections of NGF …

[HTML][HTML] P2X3 receptor mediates heat hyperalgesia in a rat model of trigeminal neuropathic pain

M Shinoda, K Kawashima, N Ozaki, H Asai… - The Journal of …, 2007 - Elsevier
The present study was undertaken to determine the role of P2X 3 receptor (P2X 3 R) on heat
hyperalgesia in a newly developed rat model of trigeminal neuropathic pain. The unilateral …

Assessment of antitumor activity and acute peripheral neuropathy of 1, 2-diaminocyclohexane platinum (II)-incorporating micelles (NC-4016)

T Ueno, K Endo, K Hori, N Ozaki, A Tsuji… - International journal …, 2014 - Taylor & Francis
Oxaliplatin, a third-generation platinum compound incorporating oxalate and 1,2-diaminocyclohexane
platinum, has been widely used in chemotherapy regimens for the treatment of …

Characterization of mechanosensitive splanchnic nerve afferent fibers innervating the rat stomach

N Ozaki, GF Gebhart - American Journal of Physiology …, 2001 - journals.physiology.org
Splanchnic nerve fibers innervating the stomach were studied in anesthetized rats; 997
fibers in the T 9 or T 10 dorsal roots were identified by electrical stimulation of the splanchnic …

Upregulations of P2X3 and ASIC3 involve in hyperalgesia induced by cisplatin administration in rats

K Hori, N Ozaki, S Suzuki, Y Sugiura - PAINŽ, 2010 - Elsevier
The role of ion channels expressed in sensory neurons on mechanical and thermal hyperalgesia
was examined in a rat model of cisplatin-induced peripheral neuropathy. The rats were …