Fas ligand in human serum

M Tanaka, T Suda, K Haze, N Nakamura, K Sato… - Nature medicine, 1996 - nature.com
The Fas ligand (FasL), a member of the tumor necrosis factor family, induces apoptosis in
Fas–bearing cells. The membrane–bound human FasL was found to be converted to a soluble …

Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum

S El-Mekkawy, MR Meselhy, N Nakamura, Y Tezuka… - Phytochemistry, 1998 - Elsevier
A new highly oxygenated triterpene named ganoderic acid α has been isolated from a
methanol extract of the fruiting bodies of Ganoderma lucidum together with twelve known …

Inhibitory effects of Sudanese medicinal plant extracts on hepatitis C virus (HCV) protease

G Hussein, H Miyashiro, N Nakamura… - … Journal Devoted to …, 2000 - Wiley Online Library
One hundred fifty‐two methanol and water extracts of different parts of 71 plants commonly
used in Sudanese traditional medicine were screened for their inhibitory effects on hepatitis …

Triterpenes from the spores of Ganoderma lucidum and their inhibitory activity against HIV-1 protease

BS Min, N Nakamura, H Miyashiro, KW Bae… - Chemical and …, 1998 - jstage.jst.go.jp
Two new lanostane-type triterpenes, lucidumol A and ganoderic acid β, were isolated from
the spores of Ganoderma (G.) lucidum, together with a new natural one and seven that were …

Triterpenes from the spores of Ganoderma lucidum and their cytotoxicity against meth-A and LLC tumor cells

BS Min, JJ Gao, N Nakamura… - Chemical and …, 2000 - jstage.jst.go.jp
Six new highly oxygenated lanostane-type triterpenes, called ganoderic acid γ (1), ganoderic
acid δ (2), ganoderic acid ε (3), ganoderic acid ζ (4), ganoderic acid η (5) and ganoderic …

Adiponectin inhibits endothelial synthesis of interleukin-8

…, R Temaru, A Sato, K Yamazaki, N Nakamura… - Circulation …, 2005 - Am Heart Assoc
Adiponectin is an antiatherogenic adipokine that inhibits inflammation by mechanisms that
are not completely understood. We explored the effect of adiponectin on endothelial …

[HTML][HTML] Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis

…, M Kawasaki, T Yatomi, N Nakamura… - The Journal of …, 1999 - Am Soc Clin Investig
The Fas ligand is predominantly expressed in activated T lymphocytes and is one of the major
effector molecules of cytotoxic T lymphocytes and natural killer cells. Previously, we found …

Pharmacokinetics of berberine and its main metabolites in conventional and pseudo germ-free rats determined by liquid chromatography/ion trap mass spectrometry

F Zuo, N Nakamura, T Akao, M Hattori - Drug Metabolism and Disposition, 2006 - ASPET
Berberine (Ber) and its main metabolites were identified and quantified using liquid
chromatography/electrospray ionization/ion trap mass spectrometry. Rat plasma contained the main …

New triterpene aldehydes, lucialdehydes A—C, from Ganoderma lucidum and their cytotoxicity against murine and human tumor cells

JJ Gao, BS Min, EM Ahn, N Nakamura… - Chemical and …, 2002 - jstage.jst.go.jp
Three new lanostante-type triterpene aldehydes, named lucialdehydes A—C (1—3), were
isolated from the fruiting bodies of Ganoderma lucidum, together with ganodermanonol (4), …

TGF-β1 as an enhancer of Fas-mediated apoptosis of lung epithelial cells

…, I Inoshima, M Yoshimi, N Nakamura… - The Journal of …, 2002 - journals.aai.org
Transforming growth factor-β1 (TGF-β1) has important roles in lung fibrosis and the potential
to induce apoptosis in several types of cells. We previously demonstrated that apoptosis of …