[HTML][HTML] Pathogenesis, early diagnosis, and therapeutic management of alcoholic liver disease

LZ Kong, N Chandimali, YH Han, DH Lee… - International journal of …, 2019 - mdpi.com
Alcoholic liver disease (ALD) refers to the damages to the liver and its functions due to
alcohol overconsumption. It consists of fatty liver/steatosis, alcoholic hepatitis, steatohepatitis, …

[HTML][HTML] Peroxiredoxin II regulates cancer stem cells and stemness-associated properties of cancers

N Chandimali, DK Jeong, T Kwon - Cancers, 2018 - mdpi.com
Cancer stem cells (CSCs) represent a sub-population of cancer cells with the ability to regulate
stemness-associated properties which are specifically responsible for unlimited growth of …

[HTML][HTML] BRM270 targets cancer stem cells and augments chemo‑sensitivity in cancer

N Chandimali, H Koh, J Kim, J Lee… - Oncology …, 2020 - spandidos-publications.com
Over the past decade, a number of studies have demonstrated the resistance of cancer cells
to conventional drugs and have recognized this as a major challenge in cancer therapy. …

[HTML][HTML] MicroRNA-128 suppresses paclitaxel-resistant lung cancer by inhibiting MUC1-C and BMI-1 in cancer stem cells

H Koh, H Park, N Chandimali, JJ Zhang, M Ghosh… - Oncotarget, 2017 - ncbi.nlm.nih.gov
The existence of cancer stem cells (CSCs) is the main reason for failure of cancer treatment
caused by drug resistance. Therefore, eradicating cancers by targeting CSCs remains a …

Combination effects of hispidin and gemcitabine via inhibition of stemness in pancreatic cancer stem cells

N Chandimali, WOOY JIN, T KWON - Anticancer Research, 2018 - ar.iiarjournals.org
Background/Aim: Natural products extracted from plants can be potent for developing
pharmaceutical products. Hispidin, a polyphenolic compound mainly derived from the medicinal …

[HTML][HTML] MicroRNA-122 negatively associates with peroxiredoxin-II expression in human gefitinib-resistant lung cancer stem cells

N Chandimali, DL Huynh, JJ Zhang, JC Lee… - Cancer Gene …, 2019 - nature.com
Previously, we demonstrated that Prx II is important for survival of the gefitinib-resistant A549
(A549/GR) cell line, an NSCLC cell line derived by repeated exposure to gefitinib. Therefore…

Shikonin-induced apoptosis of colon cancer cells is reduced by peroxiredoxin V expression

N Chandimali, HN Sun, LZ Kong, X Zhen… - Anticancer …, 2019 - ar.iiarjournals.org
Nisansala Chandimali and Hu-Nan Sun designed the experiment, performed all the
experiments, and Nisansala Chandimali, Hu-Nan Sun and Dong-Sun Lee wrote the article. Ling-Zu …

[HTML][HTML] BRM270 inhibits cancer stem cell maintenance via microRNA regulation in chemoresistant A549 lung adenocarcinoma cells

T Kwon, N Chandimali, DL Huynh, JJ Zhang… - Cell death & …, 2018 - nature.com
Chemotherapy is a standard treatment for non-small-cell lung cancer (NSCLC). However,
the dose-limiting toxicity of drugs and the development of chemoresistance are major clinical …

[HTML][HTML] Non-thermal plasma treatment improves chicken sperm motility via the regulation of demethylation levels

JJ Zhang, HL Do, N Chandimali, SB Lee, YS Mok… - Scientific Reports, 2018 - nature.com
The quality of avian semen is an important economic trait in poultry production. The present
study examines the in vitro effects of non-thermal dielectric barrier discharge plasma on …

Wogonin influences osteosarcoma stem cell stemness through ROS-dependent signaling

H Koh, HN Sun, Z Xing, R Liu, N Chandimali, T Kwon… - in vivo, 2020 - iv.iiarjournals.org
Backgorund/Aim: Wogonin, a flavonoid-like compound extracted from the root of Scutellaria
baicalensis Georgi, has been shown to have anticancer effects against cancer cells. …