Here, tumor-infiltrating CD11b + myelomonocytoid cells in murine colon adenocarcinoma-38
and GL261 murine glioma were phenotypically characterized. Over 90% were of the …

Interleukin 2 (IL)‐2 induces antitumor immunity and clinical responses in melanoma and renal
cell carcinoma. However, IL‐2 also increases the number of CD4 + CD25 + regulatory T (…

Although nanoparticles (NPs) has afforded considerable benefits in various fields of sciences,
several reports have shown their harmful effects, suggesting the necessity of adequate …

Inflammation substantially affects the risk of oral malignancy. Pro-inflammatory cytokine,
interferon (IFN)-γ, confers anti-tumor activity using several different mechanisms. Conversely, …

Background Dental pulp tissue contains many undifferentiated mesenchymal cells, which
retain the ability to differentiate into mature cells. Induced pluripotent stem cells have been …

Ligands to several Toll-like receptors (TLR), which mediate innate immune responses and
chronic inflammation have been used as adjuvants to immunotherapy to enhance their …

Two series of 1-(3-aminomethyl-4-hydroxyphenyl)-3-pyridinyl-2-propen-1-ones, designed
as novel cytotoxins, were synthesized. The compounds had low CC 50 values in the …

Purpose: In our previous study, we demonstrated that hyaluronan induces odontoblastic
differentiation of dental pulp stem cells via interactions with CD44. However, it remains unclear …

Cancer stem cells are a sub‑population of cancer cells with self‑renewal activity that play key
roles in tumor resistance to chemotherapy and radiation. Several cancer stem cell markers …

Aminomethyl derivatives of 1,5-bis(4-hydroxy-3-methoxyphenyl)penta-1,4-dien-3-one, designed
as new cytotoxins, were synthesized and evaluated in terms of their cytotoxic activities. …