Soy phytoestrogens modify DNA methylation of GSTP1, RASSF1A, EPH2 and BRCA1 promoter in prostate cancer cells

A Vardi, R Bosviel, N Rabiau, M Adjakly, S Satih… - In vivo, 2010 - iv.iiarjournals.org
Background: The aim of this study was to determine the effects of soy phytoestrogens on the
methylation of promoter genes in prostate tumors. The incidence of prostate cancer in Asia …

Odour-active compound profiles in Cantal-type cheese: Effect of cow diet, milk pasteurization and cheese ripening

A Cornu, N Rabiau, N Kondjoyan, I Verdier-Metz… - International dairy …, 2009 - Elsevier
Cantal cheese was made with either raw or pasteurized milk from cows fed either pasture or
a hay and concentrate diet, and was analyzed after 3- and 6-month aging. The cheese …

DNA repair gene ERCC2, XPC, XRCC1, XRCC3 polymorphisms and associations with bladder cancer risk in a French cohort

…, N Chalabi, F Kwiatkowski, S Satih, N Rabiau… - Anticancer …, 2008 - ar.iiarjournals.org
In polygenic diseases, association studies look for genetic variation such as polymorphisms
in low penetrance genes, ie genes in interaction with environmental factors. DNA repair …

Genistein and daidzein act on a panel of genes implicated in cell cycle and angiogenesis by polymerase chain reaction arrays in human prostate cancer cell lines

N Rabiau, M Kossaï, M Braud, N Chalabi, S Satih… - Cancer …, 2010 - Elsevier
Background: The prostate cancer most frequently affects men. The ethnic origin and family
antecedents of prostate cancer are established as risk factors. The genetic factors associated …

Genetic polymorphisms in CYP1A1, CYP1B1, COMT, GSTP1 and NAT2 genes and association with bladder cancer risk in a French cohort

L Fontana, L Delort, L Joumard, N Rabiau… - Anticancer …, 2009 - ar.iiarjournals.org
Tobacco smoking and environmental exposures are the main known risk factors for bladder
cancer (BC) via exposure to chemical carcinogens. Genetic differences in the metabolism of …

DNA methylation and soy phytoestrogens: quantitative study in DU-145 and PC-3 human prostate cancer cell lines

M Adjakly, R Bosviel, N Rabiau, JP Boiteux… - …, 2011 - Future Medicine
Aim: DNA hypermethylation is an epigenetic mechanism which induces silencing of tumor-suppressor
genes in prostate cancer. Many studies have reported that specific components of …

Gene expression profiling of breast cancer cell lines in response to soy isoflavones using a pangenomic microarray approach

S Satih, N Chalabi, N Rabiau, R Bosviel… - Omics: a journal of …, 2010 - liebertpub.com
Although the rate of breast cancer differs between women in Asian and Western countries,
molecular genetics/genomics basis of this epidemiological observation remains elusive. …

miRNAs differentially expressed in prostate cancer cell lines after soy treatment

N Rabiau, HK Trraf, M Adjakly, R Bosviel, L Guy… - in vivo, 2011 - iv.iiarjournals.org
Background: MicroRNAs (miRNAs) are small non-coding RNAs that have aberrant expression
in prostate cancer tissues. miRNAs are involved in the initiation and progression of cancer…

[HTML][HTML] DNA repair gene ERCC2 polymorphisms and associations with breast and ovarian cancer risk

…, R Bosviel, L Delort, L Fontana, A Chamoux, N Rabiau… - Molecular cancer, 2008 - Springer
Breast and ovarian cancers increased in the last decades. Except rare cases with a genetic
predisposition and high penetrance, these pathologies are viewed as a polygenic disease. …

Association between genetic polymorphisms and ovarian cancer risk

L Delort, N Chalabi, S Satih, N Rabiau… - Anticancer …, 2008 - ar.iiarjournals.org
Background: The etiology of ovarian cancer is not fully understood. Polymorphisms in low
penetrance genes involved in carcinogen and estrogen metabolism are hypothesized to play …