Dengue haemorrhagic fever and dengue shock syndrome, the most severe responses to
dengue virus (DV) infection, are characterized by plasma leakage (due to increased vascular …

Background Epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) is the
standard therapy for advanced lung adenocarcinomas with common EGFR mutations. …

Persistent high fever is one of the most typical clinical symptoms in dengue virus (DV)–infected
patients. However, the source of endogenous pyrogen (eg, IL-1β) and the signaling …

Tumor therapy by the preferential activation of a prodrug at tumor cells targeted with an
antibody−enzyme conjugate may allow improved treatment efficacy with reduced side effects. We …

In smooth muscle tissues, the relationship between muscle or cell length and active force
can be modulated by altering the cell or tissue length during stimulation. Mechanisms for this …

CLEC5A/MDL-1, a member of the myeloid C-type lectin family expressed on macrophages
and neutrophils, is critical for dengue virus (DV)-induced hemorrhagic fever and shock …

Background It is important to select appropriate targeted therapies for subgroups of patients
with lung adenocarcinoma who have specific gene alterations. Methods This prospective …

Inactivation of p53 by human papillomavirus 16/18 E6 plays a crucial role in cervical
tumorigenesis. To investigate the involvement of HPV16/18 in lung tumorigenesis, the association …

Autophagy is a self-digestive process that degrades the cytoplasmic constituents.
Immunomodulatory protein, one major bioactive component of Ganoderma, has antitumor activity. In …

BACKGROUND Lung cancer is the leading cause of cancer death in Taiwan, and the
paucity of dependable risk markers has impeded the early management of lung cancer. An …