The role of cetuximab in the induction of anticancer immune response in colorectal cancer treatment

L Holubec, J Polivka, M Safanda, M Karas… - Anticancer …, 2016 - ar.iiarjournals.org
Monoclonal antibodies binding the epidermal growth factor receptor (EGFR), such as cetuximab
or panitumumab, are widely used targeted therapeutics for the treatment of patients with …

The Role of TPS and TPA in the Diagnostics of Distant Metastases

…, D Slouka, V Simanek, M Safanda… - Anticancer …, 2016 - ar.iiarjournals.org
Aim: The aim of the study was to assess the degree to which tissue polypeptide antigen (TPA)
and tissue polypeptide-specific antigen (TPS), as well as carcinoembryonic antigen (CEA), …

Searching for new biomarkers and the use of multivariate analysis in gastric cancer diagnostics

…, V Treska, V Kulda, V Simanek, M Safanda… - Anticancer …, 2016 - ar.iiarjournals.org
Aim: The first aim of this study was to search for new biomarkers to be used in gastric cancer
diagnostics. The second aim was to verify the findings presented in literature on a sample of …

[HTML][HTML] Results of a prospective dose intensity and neutropenia prophylaxis evaluation programme (DIEPP) in cancer patients at risk of febrile neutropenia due to …

R Mądry, L Popławska, F Haslbauer, M Šafanda… - Wiener klinische …, 2016 - Springer
Objective To describe the incidence of febrile neutropenia (FN) and use of pegfilgrastim in
cancer patients with high overall risk of FN and to investigate the relationship between …

[HTML][HTML] Prospective observational study to evaluate the persistence of treatment with denosumab in patients with bone metastases from solid tumors in routine clinical …

F Haslbauer, A Petzer, M Safanda, A Tomova… - Supportive Care in …, 2020 - Springer
Purpose In the integrated analysis of phase III head-to-head trials in patients with advanced
solid tumors, denosumab demonstrated superiority over zoledronic acid in preventing …

4-years results of weekly trastuzumab and paclitaxel in the treatment of women with HER2/neu overexpressing advanced breast cancer: single institution prospective …

…, O Pribylova, M Zimovjanova, G Pazdrova, M Safanda… - Bulletin du Cancer, 2004 - jle.com
Background.–Trastuzumab is known as an active agent in HER2/neu overexpressing
advanced breast cancer. In the prospective study we investigated efficacy, safety and toxicity of …

The effectiveness of febrile neutropenia prophylaxis with lipegfilgrastim in routine clinical practice

…, J Polivka, L Lisnerova, T Kubikova, M Safanda - in vivo, 2017 - iv.iiarjournals.org
Febrile neutropenia (FN) is a common and potentially fatal complication of anticancer treatment,
particularly in patients receiving myelosuppressive chemotherapy. It has been shown …

Comparison of Chemotherapeutic Regimens Frequently Used in Metastatic Non-squamous NSCLC Treatment

…, L Koubkova, D Dolezal, M Safanda… - Anticancer …, 2021 - ar.iiarjournals.org
Background/Aim: Platinum-based chemotherapy with pemetrexed or paclitaxel/bevacizumab
are regimens used in combination with checkpoint inhibitors in non-squamous non-small …

Efficacy of weekly trastuzumab and paclitaxel in the treatment of women with HER-2/neu overexpressing metastatic breast cancer. The impact of taxane free interval …

…, M Zimovjanova, G Pazdrova, M Safanda… - Radiology and …, 2002 - radioloncol.com
Purpose. Trastuzumab is known as an active agent in HER2/neu overexpressing metastatic
breast cancer. In the prospective study we investigated efficacy, safety and toxicity of …

Progression-free survival with first line treatment as prognostic factor of treatment success in subsequent lines in lung adenocarcinoma patients–who´ s the „good …

…, O Fischer, M Zemanova, M Cernovska, M Safanda… - 2021 - Eur Respiratory Soc
Aims and objectives: In real-life practice, a proportion of lung adenocarcinoma patients exists
with good response to most of the administered drugs, resulting in favourable outcomes. …