Tumors evolve mechanisms to escape immune control by a process called immune editing,
which provides a selective pressure in the tumor microenvironment that could lead to …

Mitochondria play a crucial role in regulating cell death, which is mediated by outer membrane
permeabilization in response to death triggers such as DNA damage and growth factor …

Apoptosis is an important phenomenon in cytotoxicity induced by anticancer drugs. Here,
we review the current status of the molecular mechanisms of anticancer drug-induced …

Cancer immunosuppression evolves by constitution of an immunosuppressive network
extending from a primary tumour site to secondary lymphoid organs and peripheral vessels and …

Despite the fact that expression of Fas ligand (FasL) in cytotoxic T lymphocytes (CTLs) and in
natural killer (NK) cells plays an important role in Fas‐mediated tumor killing, During tumor …

Apoptosis is known to be an important phenomenon in exerting antitumor response to cancer
therapy, which is regulated by Bcl-2 family proteins through mitochondrial permeability …

Introduction Bcl-2 and Bcl-xL confer resistance to apoptosis, thereby reducing the effectiveness
of chemotherapy. We examined the relationship between the expression of Bcl-2 and Bcl-…

Apoptotic cells can be eliminated by phagocytosis, which is mediated by antigen-presenting
cells (APCs), such as macrophages and dendritic cells (DCs), through phosphatidylserine (…

Bcl‐2 protein plays a critical role in inhibiting anticancer drug‐induced apoptosis, which is
mediated by a mitochondria‐dependent pathway that controls the release of cytochrome c …

A number of discoveries have clarified the molecular mechanism of apoptosis, thus clarifying
the link between apoptosis and therapeutic outcome. Even though apoptosis is thought to …