[HTML][HTML] Association study on IL-4, IL-4Rα and IL-13 genetic polymorphisms in Swedish patients with colorectal cancer

L Shamoun, M Skarstedt, RE Andersson, D Wågsäter… - Clinica Chimica …, 2018 - Elsevier
Background Interleukin 4 (IL-4) and interleukin 13 (IL-13) are anti-inflammatory and
immunomodulatory cytokines which share a common cellular receptor IL4Rα and are involved in the …

Genetic variants of the IL2 gene related to risk and survival in patients with colorectal cancer

J Dimberg, L Shamoun, K Landerholm… - Anticancer …, 2019 - ar.iiarjournals.org
Background: Interleukin 2 (IL2) is a significant factor activating T-cell-mediated immune
response by stimulation of natural killer cells, T-cells and in development of regulatory T (Treg) …

[HTML][HTML] Association of gene and protein expression and genetic polymorphism of CC chemokine ligand 4 in colorectal cancer

L Shamoun, K Landerholm, AB Ramilo… - World Journal of …, 2021 - ncbi.nlm.nih.gov
BACKGROUND Leukocytes, such as T cells and macrophages, play an important role in
tumorigenesis. CC chemokine ligand (CCL) 4, which is produced by lymphocytes and …

Protein expression and genetic variation of IL32 and association with colorectal cancer in Swedish patients

L Shamoun, B Kolodziej, RE Andersson… - Anticancer …, 2018 - ar.iiarjournals.org
Background: Interleukin 32 (IL32) is an intracellular pluripotent cytokine produced by epithelial
cells, monocytes, T-lymphocytes and natural killer cells and seems to be involved in the …

[HTML][HTML] Influence of single nucleotide polymorphisms among cigarette smoking and non-smoking patients with coronary artery disease, urinary bladder cancer and …

…, M Kentsson, S Sayardoust, M Nilsson, L Shamoun… - PloS one, 2021 - journals.plos.org
Introduction Cigarette smoke is suggested to be a risk factor for coronary artery disease (CAD),
urinary bladder cancer (UBCa) or lung cancer (LCa). However, not all heavy smokers …

[HTML][HTML] Emerging role and clinical implication of mRNA scavenger decapping enzyme in colorectal cancer

J Dimberg, L Shamoun, G Johansson… - … -Research and Practice, 2024 - Elsevier
Background Turnover of RNA is a regulated process that in part controls gene expression.
This process is partly controlled by the scavenger decapping enzyme (DcpS). This study …

Single Nucleotide Polymorphism Directed Antiemetic Treatment in Women With Breast Cancer Treated With Neo-or Adjuvant Chemotherapy: A Randomised …

D Oliva, BÅ Andersson, L Shamoun, N Lewin… - Anticancer …, 2023 - ar.iiarjournals.org
Background/Aim: The role of single nucleotide polymorphisms (SNPs) in the frequency and
intensity of chemotherapy-induced nausea and vomiting (CINV) in women with breast cancer …

Cytotoxic T-lymphocyte antigen-4 (CTLA-4) gene polymorphism (rs3087243) is related to risk and survival in patients with colorectal cancer

S Van Nguyen, L Shamoun, K Landerholm… - in vivo, 2021 - iv.iiarjournals.org
Background/Aim: Cytotoxic T-lymphocyte antigen-4 (CTLA-4), transiently expressed on T
cells, plays a pivotal role in the negative feedback regulation of T-cell activation and …

[HTML][HTML] Altered IL-32 signaling in abdominal aortic aneurysm

S Bengts, L Shamoun, A Kunath, D Appelgren… - Journal of Vascular …, 2020 - karger.com
Introduction and Objective: Interleukin (IL)-32 is a pro-inflammatory cytokine not previously
studied in relation to abdominal aortic aneurysm (AAA). The aim of this study was to elucidate …

[HTML][HTML] Genetic variance and plasma concentration of CD93 is associated with cardiovascular mortality: Results from a 6.7‑year follow‑up of a healthy community …

U Alehagen, L Shamoun… - Molecular Medicine …, 2020 - spandidos-publications.com
Inflammation is one of the fundamental processes in numerous diseases. Cluster of differentiation
(CD) 93, a glycoprotein, has been reported to be associated with a number of these …