[HTML][HTML] Vitamin C—sources, physiological role, kinetics, deficiency, use, toxicity, and determination
M Doseděl, E Jirkovský, K Macáková, LK Krčmová… - Nutrients, 2021 - mdpi.com
Vitamin C (L-ascorbic acid) has been known as an antioxidant for most people. However, its
physiological role is much larger and encompasses very different processes ranging from …
physiological role is much larger and encompasses very different processes ranging from …
Vitamin K–sources, physiological role, kinetics, deficiency, detection, therapeutic use, and toxicity
P Mladěnka, K Macáková, L Kujovská Krčmová… - Nutrition …, 2022 - academic.oup.com
Vitamin K is traditionally connected with blood coagulation, since it is needed for the
posttranslational modification of 7 proteins involved in this cascade. However, it is also involved in …
posttranslational modification of 7 proteins involved in this cascade. However, it is also involved in …
[HTML][HTML] Biological Properties of Vitamins of the B-Complex, Part 1: Vitamins B1, B2, B3, and B5
M Hrubša, T Siatka, I Nejmanová, M Vopršalová… - Nutrients, 2022 - mdpi.com
This review summarizes the current knowledge on essential vitamins B 1 , B 2 , B 3 , and B
5 . These B-complex vitamins must be taken from diet, with the exception of vitamin B 3 , that …
5 . These B-complex vitamins must be taken from diet, with the exception of vitamin B 3 , that …
[HTML][HTML] Neopterin as a biomarker of immune response in cancer patients
B Melichar, M Spisarová, M Bartoušková… - Annals of …, 2017 - ncbi.nlm.nih.gov
With the advent of immunotherapy the topic of biomarkers of immune response is of high
interest. Along with the expression of programmed death ligand 1 (PD-L1) or tumor infiltrating …
interest. Along with the expression of programmed death ligand 1 (PD-L1) or tumor infiltrating …
Modern methods for vancomycin determination in biological fluids by methods based on high‐performance liquid chromatography–A review
L Javorska, LK Krcmova, D Solichova… - Journal of separation …, 2016 - Wiley Online Library
Vancomycin is a glycopeptide antibiotic used in the therapy of severe bacterial infection. The
monitoring of vancomycin levels is recommended because of its narrow therapeutic index …
monitoring of vancomycin levels is recommended because of its narrow therapeutic index …
[HTML][HTML] The antiplatelet effect of 4-methylcatechol in a real population sample and determination of the mechanism of action
M Hrubša, L Konečný, M Paclíková, MS Parvin… - Nutrients, 2022 - mdpi.com
A polyphenol-rich diet has beneficial effects on cardiovascular health. However, dietary
polyphenols generally have low bioavailability and reach low plasma concentrations. Small …
polyphenols generally have low bioavailability and reach low plasma concentrations. Small …
[HTML][HTML] Neopterin and kynurenine in serum and urine as prognostic biomarkers in hospitalized patients with delta and omicron variant SARS-CoV-2 infection
LK Krčmová, K Matoušová, L Javorská… - Clinical Chemistry and …, 2023 - degruyter.com
Objectives Currently, no biomarker or scoring system could clearly identify patients at risk of
progression to a severe coronavirus disease (COVID)-19. Even in patients with known risk …
progression to a severe coronavirus disease (COVID)-19. Even in patients with known risk …
Sex-related differences in platelet aggregation: a literature review supplemented with local data from a group of generally healthy individuals
A Carazo, M Hrubša, L Konečný… - … in Thrombosis and …, 2023 - thieme-connect.com
The process of platelet aggregation is often influenced by several factors including sex and
age. A literature review confirmed the existence of sex-related differences in platelet …
age. A literature review confirmed the existence of sex-related differences in platelet …
Simple and rapid quantification of vancomycin in serum, urine and peritoneal/pleural effusion via UHPLC–MS/MS applicable to personalized antibiotic dosing …
L Javorska, LK Krcmova, P Solich, M Kaska - Journal of Pharmaceutical …, 2017 - Elsevier
Management of the therapy of life-threatening bacterial infection is extremely based on an
optimal antibiotic treatment. Achieving the correct vancomycin dosage in blood and target …
optimal antibiotic treatment. Achieving the correct vancomycin dosage in blood and target …
[HTML][HTML] The Effect of 4-Methylcatechol on Platelets in Familial Hypercholesterolemic Patients Treated with Lipid Apheresis and/or Proprotein Convertase Subtilisin …
L Konečný, M Hrubša, J Karlíčková, A Carazo… - Nutrients, 2023 - mdpi.com
Elevated low-density lipoprotein (LDL) cholesterol levels lead to atherosclerosis and platelet
hyperaggregability, both of which are known culprits of arterial thrombosis. Normalization of …
hyperaggregability, both of which are known culprits of arterial thrombosis. Normalization of …