Mogamulizumab versus vorinostat in previously treated cutaneous T-cell lymphoma (MAVORIC): an international, open-label, randomised, controlled phase 3 trial

…, T Fenske, F Foss, N Fukuhara, P Giri, K Habe… - The lancet …, 2018 - thelancet.com
Background Cutaneous T-cell lymphomas are rare non-Hodgkin lymphomas with
substantial morbidity and mortality in advanced disease stages. We compared the efficacy of …

Human mast cell chymase cleaves pro-IL-18 and generates a novel and biologically active IL-18 fragment

Y Omoto, K Tokime, K Yamanaka, K Habe… - The Journal of …, 2006 - journals.aai.org
Increased release of IL-18 in the skin causes atopic dermatitis (AD)-like skin lesions, suggesting
a role of IL-18 in the pathogenesis of AD. Caspase-1 is a well-known activator of IL-18, …

A randomized double-blind trial of intravenous immunoglobulin for bullous pemphigoid

…, S Matsukura, M Seishima, K Habe… - Journal of …, 2017 - Elsevier
Background Patients with steroid-resistant bullous pemphigoid (BP) require an appropriate
treatment option. Objective A multicenter, randomized, placebo-controlled, double-blind trial …

Plasma ADAMTS13, von Willebrand factor (VWF) and VWF propeptide profiles in patients with DIC and related diseases

K Habe, H Wada, N Ito-Habe, T Hatada… - Thrombosis research, 2012 - Elsevier
ADAMTS13, endothelial von Willebrand factor (VWF) and related proteins are involved in
the pathogenesis of some life threatening systemic thrombotic coagulopathies. Changes of …

[HTML][HTML] IL-17A is the critical cytokine for liver and spleen amyloidosis in inflammatory skin disease

…, Y Matsushima, A Umaoka, M Kondo, K Habe… - International journal of …, 2022 - mdpi.com
Systemic amyloidosis is recognized as a serious complication of rheumatoid arthritis or
inflammatory bowel disease, but also of inflammatory skin disease. However, the detailed …

[HTML][HTML] Inflammatory skin-derived cytokines accelerate osteoporosis in mice with persistent skin inflammation

…, K Okada, A Umaoka, S Iida, K Habe… - International Journal of …, 2020 - mdpi.com
Secondary osteoporosis can also be caused by chronic inflammatory skin disease as well
as rheumatoid arthritis or inflammatory bowel disease. However, the exact role of …

[HTML][HTML] Alopecia diffusa while using interleukin-17 inhibitors against psoriasis vulgaris

M Yajima, T Akeda, M Kondo, K Habe… - Case Reports in …, 2019 - karger.com
We report two cases of alopecia diffusa during the treatment of psoriasis vulgaris with interleukin
(IL)-17 inhibitors. Psoriasis is one of the most common immune-mediated chronic skin …

[HTML][HTML] Janus kinase inhibitors ameliorated gastrointestinal amyloidosis and hypoalbuminemia in persistent dermatitis mouse model

…, Y Matsushima, A Umaoka, M Kondo, K Habe… - International Journal of …, 2021 - mdpi.com
Malnutrition is not only regarded as a complication of rheumatoid arthritis and inflammatory
bowel disease but also that of inflammatory skin disease; however, the mechanisms and …

[HTML][HTML] Inflammatory skin disease causes anxiety symptoms leading to an irreversible course

…, T Nakanishi, Y Matsushima, M Kondo, K Habe… - International journal of …, 2023 - mdpi.com
Intense itching significantly reduces the quality of life, and atopic dermatitis is associated
with psychiatric conditions, such as anxiety and depression. Psoriasis, another inflammatory …

Presence of antiphospholipid antibodies as a risk factor for thrombotic events in patients with connective tissue diseases and idiopathic thrombocytopenic purpura

K Habe, H Wada, T Matsumoto, K Ohishi, M Ikejiri… - Internal …, 2016 - jstage.jst.go.jp
Objective Antiphospholipid syndrome (APS) is a well-known complication of habitual abortion
and/or thrombosis and is frequently associated with autoimmune diseases. Methods We …