Novel Capsaicinoid-like Substances, Capsiate and Dihydrocapsiate, from the Fruits of a Nonpungent Cultivar, CH-19 Sweet, of Pepper (Capsicum annuum L.)

K Kobata, T Todo, S Yazawa, K Iwai… - Journal of agricultural …, 1998 - ACS Publications
Kenji KobataKenji Kobata - School of Food and Nutritional Sciences, University of
Shizuoka, 52-1 Yada, Shizuoka 422-8526, Japan, Graduate School of Agriculture, Kyoto …

A nonpungent component of steamed ginger—[10]-shogaol—increases adrenaline secretion via the activation of TRPV1

Y Iwasaki, A Morita, T Iwasawa, K Kobata… - Nutritional …, 2006 - Taylor & Francis
We investigated the components of ginger that are involved in increasing body temperature.
Gingerols ([6,8,10]-gingerols) and shogaols ([6,8,10]-shogaols) having different alkyl carbon …

Nordihydrocapsiate, a New Capsinoid from the Fruits of a Nonpungent Pepper, Capsicum annuum

K Kobata, K Sutoh, T Todo, S Yazawa… - Journal of natural …, 1999 - ACS Publications
A new capsiate-like substance, named nordihydrocapsiate (1), has been isolated from the
fruits of a nonpungent cultivar, CH-19 Sweet, of pepper (Capsicum annuum). The structure of …

TRPA1 agonists—allyl isothiocyanate and cinnamaldehyde—induce adrenaline secretion

Y Iwasaki, M Tanabe, K Kobata… - Bioscience …, 2008 - jstage.jst.go.jp
Thermosensitive transient receptor potential (TRP) channels, especially TRPV1 and TRPA1,
are activated by the pungent compounds present in spices. TRPV1 activation by the intake …

[HTML][HTML] Coffee extract inhibits adipogenesis in 3T3-L1 preadipocyes by interrupting insulin signaling through the downregulation of IRS1

…, R Aoyagi, F Ueda, M Kimura, K Kobata… - PloS one, 2017 - journals.plos.org
Although epidemiological data have indicated that a strong negative association exists
between coffee consumption and the prevalence of obesity-associated diseases, the molecular …

[HTML][HTML] Pyrocatechol, a component of coffee, suppresses LPS-induced inflammatory responses by inhibiting NF-κB and activating Nrf2

…, Y Ishihara, A Sakai, M Matsutaka, K Kobata… - Scientific reports, 2020 - nature.com
Coffee is a complex mixture of many bioactive compounds possessing anti-inflammatory
properties. However, the mechanisms by which coffee exerts anti-inflammatory effects remains …

Anti-Glycation Effects of Pomegranate (Punica granatum L.) Fruit Extract and Its Components in Vivo and in Vitro

…, N Nishida, Y Matsuura, K Kobata… - Journal of agricultural …, 2015 - ACS Publications
Accumulation of advanced glycation end products (AGEs) leads to various diseases such
as diabetic complications and arteriosclerosis. In this study, we examined the effect of …

[HTML][HTML] Transcranial magnetic stimulation-induced global propagation of transient phase resetting associated with directional information flow

M Kawasaki, Y Uno, J Mori, K Kobata… - Frontiers in human …, 2014 - frontiersin.org
Electroencephalogram (EEG) phase synchronization analyses can reveal large-scale
communication between distant brain areas. However, it is not possible to identify the directional …

Capsinoid Is Biosynthesized from Phenylalanine and Valine in a Non-Pungent Pepper, Capsicum annuum L. cv. CH-19 Sweet

K Sutoh, K Kobata, S Yazawa… - Bioscience …, 2006 - Taylor & Francis
The biosynthetic pathway of capsinoid in ‘CH-19 Sweet’ was investigated. [ 3 H]Valine and [
14 C]phenylalanine were injected into the fruits of the intact plant. Both of radioactivities …

Enzymatic synthesis of a capsinoid by the acylation of vanillyl alcohol with fatty acid derivatives catalyzed by lipases

K Kobata, M Kawaguchi… - Bioscience, biotechnology …, 2002 - academic.oup.com
Capsinoids are a novel group of compounds produced by the Capsicum plant. We
synthesized a capsinoid by the lipase-catalyzed esterification of vanillyl alcohol with fatty acid …