Inflammatory bowel disease (IBD) is a general term for chronic or remitting/relapsing inflammatory
diseases of the intestinal tract and generally refers to ulcerative colitis (UC) and Crohn’…

Background & Aims A random biopsy is recommended for surveillance of ulcerative colitis (UC)-associated
colorectal cancer. However, a targeted biopsy might be more effective. We …

To assess the role of microRNAs (miR) in hepatocellular carcinoma (HCC), we performed
comprehensive microRNA expression profiling using HCC cell lines and identified miR-93 as …

Melanoma brain metastasis (MBM) represents a frequent complication of cutaneous melanoma.
Despite aggressive multi-modality therapy, patients with MBM often have a survival rate …

BACKGROUND: Oncological outcomes of lateral pelvic lymph node metastasis in rectal cancer
treated with preoperative chemoradiotherapy remain to be elucidated. OBJECTIVE: The …

Background Curative resection of sigmoid colon and rectal cancer includes “high tie” of the
inferior mesenteric artery (IMA). However, IMA ligation compromises blood flow to the …

Most T1 colorectal cancers treated by radical surgery can now be cured by endoscopic
submucosal dissection. Although 70%−80% of T1 colorectal cancers are classified as high risk, <…

Tumor molecular profiling is becoming a standard of care for patients with cancer, but the
optimal platform for cancer sequencing remains undetermined. We established a …

Colorectal cancer ( CRC ) is one of the most common cancers globally as well as in Japan
and has shown a pattern of increasing incidence and mortality rates. Therefore, guidelines for …

Restorative proctocolectomy with ileal pouch‐anal anastomosis has been the surgical treatment
of choice for patients with ulcerative colitis who require surgery. Quality of life after this …