Anti-obesity effects of three major components of green tea, catechins, caffeine and theanine, in mice

G Zheng, K Sayama, T Okubo, LR Juneja, I Oguni - In vivo, 2004 - iv.iiarjournals.org
To elucidate the anti-obesity effects of three major components of green tea, catechins, caffeine
and theanine, female ICR mice were fed on diets containing 2% green tea powder and …

Characterization of the estrogenic activities of zearalenone and zeranol in vivo and in vitro

H Takemura, JY Shim, K Sayama, A Tsubura… - The Journal of steroid …, 2007 - Elsevier
In the present study, we compared the estrogenic activity of zearalenone (ZEN) and zeranol
(ZOL) by determining their relative receptor binding affinities for human ERα and ERβ and …

[PDF][PDF] Regulation of telomere length by G-quadruplex telomere DNA-and TERRA-binding protein TLS/FUS

…, A Takada, S Tada, M Shimizu, K Sayama… - Chemistry & biology, 2013 - cell.com
Mammalian telomeres comprise noncoding TTAGGG repeats in double-stranded regions with
a single-stranded TTAGGG repeat 3′ overhang and are bound by a multiprotein complex …

In vitro and in vivo estrogenic activity of chlorinated derivatives of bisphenol A

H Takemura, J Ma, K Sayama, Y Terao, BT Zhu… - Toxicology, 2005 - Elsevier
The estrogenic activity of bisphenol A (BPA) and its chlorinated derivatives, 2-(3-chloro-4-hydroxyphenyl)-2-(4-hydroxyphenyl)propane
(3-ClBPA) and 2,2-bis(3-chloro-4-hydroxyphenyl)…

[HTML][HTML] Catechins and caffeine inhibit fat accumulation in mice through the improvement of hepatic lipid metabolism

…, T Moriyama, S Ozasa, T Kawada, K Sayama - Journal of …, 2012 - hindawi.com
To elucidate the inhibiting mechanisms of fat accumulation by catechins, caffeine, and
epigallocatechin gallate (EGCG), ICR mice were fed diets containing either 0.3% catechins or 0.1…

Maternal prolactin during late pregnancy is important in generating nurturing behavior in the offspring

…, I Amano, Y Takatsuru, K Sayama… - Proceedings of the …, 2017 - National Acad Sciences
Although maternal nurturing behavior is extremely important for the preservation of a species,
our knowledge of the biological underpinnings of these behaviors is insufficient. Here we …

Effects of catechins and caffeine on the development of atherosclerosis in mice

…, Y Matsushima, Y Kawai, K Sayama - Bioscience …, 2017 - academic.oup.com
Atherosclerosis is one of the diseases related to metabolic syndrome which is caused by
obesity. Previous reports have shown that green tea and its components have anti-obesity effect…

[HTML][HTML] Downregulation of chemokine receptor 9 facilitates CD4+CD8αα+ intraepithelial lymphocyte development

…, S Tanemoto, Y Koda, J Zheng, K Sayama… - Nature …, 2023 - nature.com
Intestinal intraepithelial lymphocytes (IELs) reside in the gut epithelial layer, where they help
in maintaining intestinal homeostasis. Peripheral CD4 + T cells can develop into CD4 + …

Green tea extract-induced acute hepatotoxicity in rats

…, M Yuki, T Yuri, Y Yoshikawa, K Sayama… - Journal of toxicologic …, 2014 - jstage.jst.go.jp
Although green tea is considered to be a healthy beverage, hepatotoxicity associated with
the consumption of green tea extract has been reported. In the present study, we …

Social isolation stress induces hepatic hypertrophy in C57BL/6J mice

…, K Motoyama, A Matsui, K Sayama… - The Journal of …, 2012 - jstage.jst.go.jp
We previously reported that social isolation stimulated a stress response leading to increasing
plasma corticosterone level and disruption of the hepatic lipid metabolism-related pathway…