[HTML][HTML] Vitamin A update: forms, sources, kinetics, detection, function, deficiency, therapeutic use and toxicity

A Carazo, K Macáková, K Matoušová, LK Krčmová… - Nutrients, 2021 - mdpi.com
Vitamin A is a group of vital micronutrients widely present in the human diet. Animal-based
products are a rich source of the retinyl ester form of the vitamin, while vegetables and fruits …

[HTML][HTML] Biological Properties of Vitamins of the B-Complex, Part 1: Vitamins B1, B2, B3, and B5

…, M Vopršalová, L Kujovská Krčmová, K Matoušová… - Nutrients, 2022 - mdpi.com
This review summarizes the current knowledge on essential vitamins B 1 , B 2 , B 3 , and B
5 . These B-complex vitamins must be taken from diet, with the exception of vitamin B 3 , that …

[HTML][HTML] The antiplatelet effect of 4-methylcatechol in a real population sample and determination of the mechanism of action

…, F Musil, J Karlíčková, L Javorská, K Matoušová… - Nutrients, 2022 - mdpi.com
A polyphenol-rich diet has beneficial effects on cardiovascular health. However, dietary
polyphenols generally have low bioavailability and reach low plasma concentrations. Small …

[HTML][HTML] Neopterin and kynurenine in serum and urine as prognostic biomarkers in hospitalized patients with delta and omicron variant SARS-CoV-2 infection

LK Krčmová, K Matoušová, L Javorská… - Clinical Chemistry and …, 2023 - degruyter.com
Objectives Currently, no biomarker or scoring system could clearly identify patients at risk of
progression to a severe coronavirus disease (COVID)-19. Even in patients with known risk …

Sex-related differences in platelet aggregation: a literature review supplemented with local data from a group of generally healthy individuals

…, J Karlíčková, L Javorská, K Matoušová… - … in Thrombosis and …, 2023 - thieme-connect.com
The process of platelet aggregation is often influenced by several factors including sex and
age. A literature review confirmed the existence of sex-related differences in platelet …

[HTML][HTML] The Effect of 4-Methylcatechol on Platelets in Familial Hypercholesterolemic Patients Treated with Lipid Apheresis and/or Proprotein Convertase Subtilisin …

…, J Karlíčková, A Carazo, L Javorská, K Matoušová… - Nutrients, 2023 - mdpi.com
Elevated low-density lipoprotein (LDL) cholesterol levels lead to atherosclerosis and platelet
hyperaggregability, both of which are known culprits of arterial thrombosis. Normalization of …

Analysis of vitamin K1 and major K2 variants in rat/human serum and lipoprotein fractions by a rapid, simple, and sensitive UHPLC-MS/MS method

K Mrštná, K Matoušová, LK Krčmová, A Carazo… - … of Chromatography A, 2024 - Elsevier
Determination of the various forms of vitamin K, which are involved in coagulation and other
physiological processes in humans, is challenging and no standardized method is yet …

[HTML][HTML] Evaluation of inflammatory biomarkers and vitamins in hospitalized patients with SARS-CoV-2 infection and post-COVID syndrome

LK Krčmová, L Javorská, K Matoušová… - Clinical Chemistry and …, 2024 - degruyter.com
Objectives Concentrations of neopterin, kynurenine and kynurenine/tryptophan ratios
predict prognosis and the need for oxygen therapy in patients hospitalized for severe acute …

Head-to-head ex vivo comparison of clinically used direct anticoagulant drugs

…, P Skořepa, F Musil, L Javorská, K Matoušová… - Naunyn-Schmiedeberg's …, 2023 - Springer
An imbalance in coagulation is associated with cardiovascular events. For prevention and
treatment, anticoagulants, currently mainly xabans and gatrans, are used. The purpose of the …

Biomarkers of inflammation and progression during immunotherapy in patients with metastatic renal cell carcinoma

…, J Juranova, A Zemankova, T Adam, K Matousova… - in vivo, 2023 - iv.iiarjournals.org
Background/Aim: Biomarkers that would identify patients unlikely to respond to immunotherapy
with immune checkpoint inhibitors (ICIs) remain an unmet medical need. Patients and …