Lamivudine is effective to control hepatitis B virus (HBV) reactivation in HBV‐carrying
cancer patients who undergo chemotherapy, but the optimal treatment protocol remains …

Background The pathogenesis of multiple myeloma involves complex genetic and epigenetic
events. This study aimed to investigate the role and clinical relevance of the long non-…

Disruption of circadian rhythm is believed to play a critical role in cancer development. To
gain further insights into the roles of circadian genes in chronic myeloid leukemia (CML), we …

Cancer commonly occurs in the elderly and immunotherapy (IT) is being increasingly applied
to this population. However, the majority of preclinical mouse tumor models assessing …

Background Gastric cancer (GC), an aggressive malignant tumor of the alimentary tract, is a
leading cause of cancer-related death. Circadian rhythm exhibits a 24-hour variation in …

Circadian clock genes use transcriptional-translational feedback loops to control circadian
rhythms. Recent studies have demonstrated that expression of some circadian clock genes …

Exogenous arginine is required for growth in some argininosuccinate synthetase (ASS)-deficient
cancers. Arginine deiminase (ADI) inhibits growth in various ASS-deficient cancers by …

Background Cellular senescence is a specialized form of growth arrest that is generally
irreversible. Upregulated p16, p53, and p21 expression and silencing of E2F target genes have …

Multiple myeloma is a hematologic malignancy of plasma cells that causes bone-destructive
lesions and associated skeletal-related events (SREs). The pathogenesis of myeloma-…

Background/Aims Vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
is one of the best policies to control COVID-19 pandemic. The serological …