[HTML][HTML] Pathogenesis, early diagnosis, and therapeutic management of alcoholic liver disease

…, JS Kim, SU Kim, TD Kim, DK Jeong, HN Sun… - International journal of …, 2019 - mdpi.com
Alcoholic liver disease (ALD) refers to the damages to the liver and its functions due to
alcohol overconsumption. It consists of fatty liver/steatosis, alcoholic hepatitis, steatohepatitis, …

Human microRNA-27a* targets Prf1 and GzmB expression to regulate NK-cell cytotoxicity

TD Kim, SU Lee, S Yun, HN Sun… - Blood, The Journal …, 2011 - ashpublications.org
Perforin (Prf1) and granzyme B (GzmB) are essential effector molecules for natural killer (NK)–cell
cytotoxicity, but how Prf1 and GzmB expression is regulated during arming of NK cells …

Characterization of neural cell types expressing peroxiredoxins in mouse brain

MH Jin, YH Lee, JM Kim, HN Sun, EY Moon… - Neuroscience …, 2005 - Elsevier
The differential expression patterns of antioxidant enzymes observed in the brains of patients
with neurodegenerative diseases suggest an important role for reactive oxygen species …

Curcumin activates ROS signaling to promote pyroptosis in hepatocellular carcinoma HepG2 cells

WF Liang, YX Gong, HF Li, FL Sun, WL Li, D Chen… - in vivo, 2021 - iv.iiarjournals.org
Background/Aim: Curcumin is a polyphenol that exerts a variety of pharmacological activities
and plays an anti-cancer role in many cancer cells. It was recently reported that gasdermin …

Peroxiredoxin I is a ROS/p38 MAPK-dependent inducible antioxidant that regulates NF-κB-mediated iNOS induction and microglial activation

SU Kim, YH Park, JS Min, HN Sun, YH Han… - Journal of …, 2013 - Elsevier
Reactive oxygen species (ROS) function as modulators of pro-inflammatory processes in
microglia-associated neurodegenerative diseases. However, little is known about the …

[HTML][HTML] PRDX1 negatively regulates bleomycin-induced pulmonary fibrosis via inhibiting the epithelial-mesenchymal transition and lung fibroblast proliferation in vitro …

HN Sun, CX Ren, DH Lee, WH Wang, XY Guo… - Cellular & Molecular …, 2023 - Springer
Hu-Nan Sun … on request from the corresponding author (Hu-Nan Sun), upon
reasonable request. … Yue J, Sun B, Liu G, Mulder KM. Requirement of TGF-beta receptor-dependent …

[HTML][HTML] Regulation of anoikis by extrinsic death receptor pathways

YH Han, Y Wang, SJ Lee, MH Jin, HN Sun… - Cell Communication and …, 2023 - Springer
Metastatic cancer cells can develop anoikis resistance in the absence of substrate
attachment and survive to fight tumors. Anoikis is mediated by endogenous mitochondria-dependent …

Novel 1, 4-naphthoquinone derivatives induce apoptosis via ROS-mediated p38/MAPK, Akt and STAT3 signaling in human hepatoma Hep3B cells

…, H Wang, WT Xu, JQ Li, Y Liu, YQ Wu, HN Sun… - … International Journal of …, 2018 - Elsevier
4-Naphthoquinone and its derivatives have shown some efficacy as therapeutic compounds
for cancer and inflammation, though their clinical application is limited by their side-effects. …

Microglial peroxiredoxin V acts as an inducible anti‐inflammatory antioxidant through cooperation with redox signaling cascades

HN Sun, SU Kim, SM Huang, JM Kim… - Journal of …, 2010 - Wiley Online Library
Microglial peroxiredoxin V acts as an inducible anti‐inflammatory antioxidant through cooperation
with redox signaling cascades - Sun - 2010 - Journal of … Hu-Nan SunHu-Nan Sun

Non-thermal plasma-activated medium induces apoptosis of Aspc1 cells through the ROS-dependent autophagy pathway

X Zhen, HN Sun, R Liu, HS Choi, DS Lee - in vivo, 2020 - iv.iiarjournals.org
Background/Aim: Numerous studies on various cancer cell lines have reported that direct
exposure to non-thermal plasma treatment using plasma-activated medium (PAM) can be …