Spectrum of Epstein-Barr virus-related diseases: a pictorial review

…, N Hayashi, S Aoki, M Minami, H Uozaki… - Japanese journal of …, 2009 - Springer
Epstein-Barr virus (EBV) prevails among more than 90% of the adult population worldwide.
Most primary infections occur during young childhood and cause no or only nonspecific …

Epstein–Barr virus and gastric carcinoma: virus–host interactions leading to carcinoma

M Fukayama, R Hino, H Uozaki - Cancer science, 2008 - Wiley Online Library
Epstein–Barr virus (EBV)‐associated gastric carcinoma (GC) is a distinct subgroup of GC,
comprising 10% of all cases of GC. EBV‐associated carcinoma is the monoclonal growth of …

Activation of DNA Methyltransferase 1 by EBV Latent Membrane Protein 2A Leads to Promoter Hypermethylation of PTEN Gene in Gastric Carcinoma

R Hino, H Uozaki, N Murakami, T Ushiku, A Shinozaki… - Cancer research, 2009 - AACR
CpG island promoter methylation of tumor suppressor genes is one of the most characteristic
abnormalities in EBV-associated gastric carcinoma (GC). Aberrant promoter methylation …

Classification of Epstein–Barr virus–positive gastric cancers by definition of DNA methylation epigenotypes

…, G Nagae, T Ushiku, Y Kikuchi, R Hino, H Uozaki… - Cancer research, 2011 - AACR
Epstein–Barr virus (EBV) is associated with Burkitt lymphoma, nasopharyngeal carcinoma,
opportunistic lymphomas in immunocompromised hosts, and a fraction of gastric cancers. …

CpG island methylation status in gastric carcinoma with and without infection of Epstein-Barr virus

MS Chang, H Uozaki, JM Chong, T Ushiku… - Clinical Cancer …, 2006 - AACR
Purpose: EBV-associated gastric carcinoma shows global CpG island methylation of the
promoter region of various cancer-related genes. To further clarify the significance of CpG …

Downregulation of microRNA-200 in EBV-associated gastric carcinoma

…, T Ushiku, R Hino, M Isogai, S Ishikawa, H Uozaki… - Cancer Research, 2010 - AACR
EBV-associated gastric carcinoma is a distinct gastric carcinoma subtype with characteristic
morphologic features similar to those of cells that undergo epithelial-to-mesenchymal …

[HTML][HTML] Epstein-Barr virus and gastric carcinoma–viral carcinogenesis through epigenetic mechanisms

H Uozaki, M Fukayama - International journal of clinical and …, 2008 - ncbi.nlm.nih.gov
Epstein-Barr virus (EBV)-associated gastric carcinoma (GC) is the monoclonal growth of
EBV-infected epithelial cells, and the entity was recognized only recently. EBV-associated GC is …

Overexpression of resistance‐related proteins (metallothioneins, glutathione‐S‐transferase π, heat shock protein 27, and lung resistance‐related protein) in …

H Uozaki, H Horiuchi, T Ishida, T Iijima… - … Journal of the …, 1997 - Wiley Online Library
BACKGROUND The prognosis for patients with osteosarcoma has improved over the past 20
years, mainly due to developments in chemotherapy. Some proteins have been reported to …

Glypican 3‐expressing gastric carcinoma: Distinct subgroup unifying hepatoid, clear‐cell, and α‐fetoprotein‐producing gastric carcinomas

T Ushiku, H Uozaki, A Shinozaki, S Ota… - Cancer …, 2009 - Wiley Online Library
Gypican‐3 (GPC3) has been recognized as an oncofetal protein in hepatic neoplasms and
yolk sac tumors. To characterize a distinct subgroup of gastric carcinoma (GC) expressing …

ARID1A expression loss in gastric cancer: pathway-dependent roles with and without Epstein–Barr virus infection and microsatellite instability

…, K Matsusaka, A Kunita, T Ushiku, H Uozaki… - Virchows Archiv, 2012 - Springer
The AT-rich interactive domain 1A gene (ARID1A), which encodes one of the subunits in the
Switch/Sucrose Nonfermentable chromatin remodeling complex, carries mutations and is …