User profiles for FUMIHITO ONO
Fumihito OnoProfessor of Physiology, Osaka Medical College Verified email at osaka-med.ac.jp Cited by 1640 |
Identification of adult nephron progenitors capable of kidney regeneration in zebrafish
Loss of kidney function underlies many renal diseases 1 . Mammals can partly repair their
nephrons (the functional units of the kidney), but cannot form new ones 2 , 3 . By contrast, fish …
nephrons (the functional units of the kidney), but cannot form new ones 2 , 3 . By contrast, fish …
[HTML][HTML] “Slow” skeletal muscles across vertebrate species
VM Luna, E Daikoku, F Ono - Cell & bioscience, 2015 - Springer
Skeletal muscle fibers are generally classified into two groups: slow (type I) and fast (type II).
Fibers in each group are uniquely designed for specific locomotory needs based on their …
Fibers in each group are uniquely designed for specific locomotory needs based on their …
Paralytic zebrafish lacking acetylcholine receptors fail to localize rapsyn clusters to the synapse
F Ono, S Higashijima, A Shcherbatko… - Journal of …, 2001 - Soc Neuroscience
Physiological analysis of two lines of paralytic mutant zebrafish,relaxed and sofa potato,
reveals defects in distinct types of receptors in skeletal muscle. In sofa potato the paralysis …
reveals defects in distinct types of receptors in skeletal muscle. In sofa potato the paralysis …
[HTML][HTML] Voltage-dependent sodium channel function is regulated through membrane mechanics
Cut-open recordings from Xenopus oocytes expressing either nerve (PN1) or skeletal muscle
(SkM1) Na + channel α subunits revealed slow inactivation onset and recovery kinetics of …
(SkM1) Na + channel α subunits revealed slow inactivation onset and recovery kinetics of …
[PDF][PDF] Tethering naturally occurring peptide toxins for cell-autonomous modulation of ion channels and receptors in vivo
The physiologies of cells depend on electrochemical signals carried by ion channels and
receptors. Venomous animals produce an enormous variety of peptide toxins with high affinity …
receptors. Venomous animals produce an enormous variety of peptide toxins with high affinity …
The nicotinic acetylcholine receptors of zebrafish and an evaluation of pharmacological tools used for their study
RL Papke, F Ono, C Stokes, JM Urban… - Biochemical …, 2012 - Elsevier
Zebrafish (Danio rerio) have been used to study multiple effects of nicotine, for example on
cognition, locomotion, and stress responses, relying on the assumption that pharmacological …
cognition, locomotion, and stress responses, relying on the assumption that pharmacological …
[HTML][HTML] Increased BUB1B/BUBR1 expression contributes to aberrant DNA repair activity leading to resistance to DNA-damaging agents
…, K Hirata, H Hirano, H Nomi, Y Hirose, F Ono… - Oncogene, 2021 - nature.com
There has been accumulating evidence for the clinical benefit of chemoradiation therapy (CRT),
whereas mechanisms in CRT-recurrent clones derived from the primary tumor are still …
whereas mechanisms in CRT-recurrent clones derived from the primary tumor are still …
The zebrafish motility mutant twitch once reveals new roles for rapsyn in synaptic function
F Ono, A Shcherbatko, S Higashijima… - Journal of …, 2002 - Soc Neuroscience
Upon touch, twitch once zebrafish respond with one or two swimming strokes instead of
typical full-blown escapes. This use-dependent fatigue is shown to be a consequence of a …
typical full-blown escapes. This use-dependent fatigue is shown to be a consequence of a …
[HTML][HTML] Mutation in the intracellular chloride channel CLCC1 associated with autosomal recessive retinitis pigmentosa
We identified a homozygous missense alteration (c.75C>A, p.D25E) in CLCC1, encoding a
presumptive intracellular chloride channel highly expressed in the retina, associated with …
presumptive intracellular chloride channel highly expressed in the retina, associated with …
[HTML][HTML] Multiple alterations in glutamatergic transmission and dopamine D2 receptor splicing in induced pluripotent stem cell-derived neurons from patients with …
An increasing body of evidence suggests that impaired synapse development and function
are associated with schizophrenia; however, the underlying molecular pathophysiological …
are associated with schizophrenia; however, the underlying molecular pathophysiological …